Evidence map›Paper›PMID 34443950›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Antiviral Efficacy of Metal and Metal Oxide Nanoparticles against the Porcine Reproductive and Respiratory Syndrome Virus.

Simon P Graham, Yuen-Ki Cheong, Summer Furniss, Emma Nixon, Joseph A Smith, Xiuyi Yang, Rieke Fruengel, Sabha Hussain, Monika A Tchorzewska, Roberto M La Ragione and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Effect of BIO-PLYViruses · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simon P GrahamSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.ORCID 0000-0003-4852-405X
Yuen-Ki CheongSchool of Physics, Engineering and Computer Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.ORCID 0000-0002-3737-6285
Summer FurnissSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Emma NixonSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.ORCID 0000-0002-6570-4928
Joseph A SmithSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Xiuyi YangSchool of Physics, Engineering and Computer Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Rieke FruengelSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Sabha HussainSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Monika A TchorzewskaSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Roberto M La RagioneSchool of Veterinary Medicine, University of Surrey, Guildford GU2 7AL, UK.
Guogang RenSchool of Physics, Engineering and Computer Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.ORCID 0000-0001-8865-1526

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Engineering and Physical Sciences Research Council EP/N034368/1
6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome viruses (PRRSV) are responsible for one of the most economically important diseases affecting the global pig industry. On-farm high-efficiency particulate air (HEPA) filtration systems can effectively reduce airborne transmission of PRRSV and the incidence of PRRS, but they are costly, and their adoption is limited. Therefore, there is a need for low-cost alternatives, such as antimicrobial filters impregnated with antiviral nanoparticles (AVNP). During the past 10 years, tailored intermetallic/multi-elemental AVNP compositions have demonstrated effective performance against human viruses. In this study, a panel of five AVNP was evaluated for viricidal activity against PRRSV. Three AVNP materials: AVNP2, copper nanoparticles (CuNP), and copper oxide nanoparticles (CuONP), were shown to exert a significant reduction (>99.99%) in virus titers at 1.0% (

Indexed as

antiviral nanoparticleporcine reproductive and respiratory syndrome virusStaphylococcus aureusviricidal efficacy

Identifiers

PMID34443950
PMCPMC8398903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.