Evidence map›Paper›PMID 34443939›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Laser Scribing Fabrication of Graphitic Carbon Biosensors for Label-Free Detection of Interleukin-6.

Pei Shee Tan, Eoghan Vaughan, Jahidul Islam, Niall Burke, Daniela Iacopino, Joanna B Tierney

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pei Shee TanShannon Applied Biotechnology Centre, Munster Technological University, Tralee, V92KA43 Kerry, Ireland.ORCID 0000-0002-1751-2999
Eoghan VaughanTyndall National Institute, University College Cork, Dyke Parade, T12R5CP Cork, Ireland.ORCID 0000-0002-9524-0204
Jahidul IslamTyndall National Institute, University College Cork, Dyke Parade, T12R5CP Cork, Ireland.
Niall BurkeShannon Applied Biotechnology Centre, Munster Technological University, Tralee, V92KA43 Kerry, Ireland.
Daniela IacopinoTyndall National Institute, University College Cork, Dyke Parade, T12R5CP Cork, Ireland.ORCID 0000-0003-2301-9401
Joanna B TierneyShannon Applied Biotechnology Centre, Munster Technological University, Tralee, V92KA43 Kerry, Ireland.
Shannon Applied Biotechnology Centre · IEUniversity College Cork · IE

Funding

Horizon 2020 814496Research Bursary Programme Munster Technological University N/AScience Foundation Ireland 16/RC/3835
6 · The paper itself

Abstract

Interleukin-6 (IL-6) is an important immuno-modulating cytokine playing a pivotal role in inflammatory processes in disease induction and progression. As IL-6 serves as an important indicator of disease state, it is of paramount importance to develop low cost, fast and sensitive improved methods of detection. Here we present an electrochemical immunosensor platform based on the use of highly porous graphitic carbon electrodes fabricated by direct laser writing of commercial polyimide tapes and chemically modified with capture IL-6 antibodies. The unique porous and 3D morphology, as well as the high density of edge planes of the graphitic carbon electrodes, resulted in a fast heterogeneous electron transfer (HET) rate, k

Indexed as

direct laser writingelectrochemical immunosensorELISAgraphitic carbonIL-6inflammation

Identifiers

PMID34443939
PMCPMC8399033
OpenAlexW3194606916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.