ArticleNanomaterials (Basel, Switzerland)2021
Poly(methacrylic Acid)-Cellulose Brushes as Anticancer Porphyrazine Carrier.
Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Specifics of Pharmacokinetics and Biodistribution of 5-Fluorouracil Polymeric Complex.Molecules (Basel, Switzerland) · 2023Article
- A Polyelectrolyte Colloidal Brush Based on Cellulose: Perspectives for Future Applications.Polymers · 2023Article
- Cyanoarylporphyrazine dyes: multimodal compounds for personalised photodynamic therapy.Biophysical reviews · 2023Review
- Comparative Analysis of Tetra(2-naphthyl)tetracyano-porphyrazine and Its Iron Complex as Photosensitizers for Anticancer Photodynamic Therapy.Pharmaceutics · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The prospective strategy for treatment of cancer is based on the application of nano-sized macromolecular carriers, which are able penetrate inside and can be accumulated within tumor tissue. In this work graft copolymers of cellulose and poly(methacrylic acid) has been prepared and tested as a nanocontainers for the delivery of drug to tumor. For this purpose, two derivatives of porphyrazine suitable for photodynamic cancer therapy were loaded into prepared polymer brush. Fluorescence imaging was applied for monitoring of accumulation of porphyrazine in the CT26 murine colon carcinoma. The selective accumulation of cellulose brush loaded with porphyrazine in tumor was demonstrated by fluorescence intensity contrast between the tumor area and normal tissues. The tumor growth rate after photodynamic therapy were assessed and inhibition of its growth was revealed.
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Registered trials
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