Evidence map›Paper›PMID 34443796›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Facile Construction of a Solely-DNA-Based System for Targeted Delivery of Nucleic Acids.

Ziwen Dai, Juan Li, Yongfang Lin, Zhigang Wang, Yang Huang

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ziwen DaiCollege of Materials Science and Engineering, Shenzhen University, Shenzhen 518055, China.
Juan LiSchool of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen 518055, China.
Yongfang LinSchool of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen 518055, China.
Zhigang WangSchool of Pharmaceutical Sciences, Health Science Center, Shenzhen University, Shenzhen 518055, China.ORCID 0000-0003-1025-4664
Yang HuangCollege of Materials Science and Engineering, Shenzhen University, Shenzhen 518055, China.

Funding

Shenzhen Science and Technology Innovation Commission Project JCYJ20170412113009742.SZU Top Ranking Project 86000000210
6 · The paper itself

Abstract

We designed a functional drug delivery system based solely on DNA. The whole system was built with only four DNA strands. Cyclization of DNA strands excluded the formation of byproducts. DNA aptamers were equipped to endow triangular DNA nanostructures with targeting ability. The homogeneity of materials enabled not only facile construction but also convenient loading of nucleic acid-based drugs with much ease.

Indexed as

DNA aptamerDNA nanostructuretargeted drug delivery

Identifiers

PMID34443796
PMCPMC8398070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.