Evidence map›Paper›PMID 34443722›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Electrochemical Response of Glucose Oxidase Adsorbed on Laser-Induced Graphene.

Sónia O Pereira, Nuno F Santos, Alexandre F Carvalho, António J S Fernandes, Florinda M Costa

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sónia O Pereirai3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4174-7253
Nuno F Santosi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.
Alexandre F Carvalhoi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.
António J S Fernandesi3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.
Florinda M Costai3N, Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-8729-714X
University of Aveiro · PT

Funding

Fundação para a Ciência e a Tecnologia BPD/UI96/5177/2020Fundação para a Ciência e a Tecnologia BPD/UI96/5808/2017Fundação para a Ciência e a Tecnologia DAEPHYS-FCT PD/BD/114063/2015Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-028755Fundação para a Ciência e a Tecnologia UIDB/50025/2020Fundação para a Ciência e a Tecnologia UIDP/50025/2020
6 · The paper itself

Abstract

Carbon-based electrodes have demonstrated great promise as electrochemical transducers in the development of biosensors. More recently, laser-induced graphene (LIG), a graphene derivative, appears as a great candidate due to its superior electron transfer characteristics, high surface area and simplicity in its synthesis. The continuous interest in the development of cost-effective, more stable and reliable biosensors for glucose detection make them the most studied and explored within the academic and industry community. In this work, the electrochemistry of glucose oxidase (GOx) adsorbed on LIG electrodes is studied in detail. In addition to the well-known electroactivity of free flavin adenine dinucleotide (FAD), the cofactor of GOx, at the expected half-wave potential of -0.490 V vs. Ag/AgCl (1 M KCl), a new well-defined redox pair at 0.155 V is observed and shown to be related to LIG/GOx interaction. A systematic study was undertaken in order to understand the origin of this activity, including scan rate and pH dependence, along with glucose detection tests. Two protons and two electrons are involved in this reaction, which is shown to be sensitive to the concentration of glucose, restraining its origin to the electron transfer from FAD in the active site of GOx to the electrode via direct or mediated by quinone derivatives acting as mediators.

Indexed as

cyclic voltammetryelectron transferflavin adenine dinucleotide (FAD)Glucose Oxidase (GOx)Laser-Induced Graphene (LIG)

Identifiers

PMID34443722
PMCPMC8401569
OpenAlexW3183948877

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.