Evidence map›Paper›PMID 34443710›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Nano-Biomaterials for Retinal Regeneration.

Rahul Sharma, Deepti Sharma, Linda D Hazlett, Nikhlesh K Singh

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Nanotechnology-Based Treatment for Ophthalmic Diseases.International journal of nanomedicine · 2026
    Review
  2. Article
  3. Nanotherapy for Neural Retinal Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  4. Review
  5. Annexin A1 in the nervous and ocular systems.Neural regeneration research · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rahul SharmaIntegrative Biosciences Center, Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-5925-9848
Deepti SharmaIntegrative Biosciences Center, Wayne State University, Detroit, MI 48202, USA.
Linda D HazlettDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI 48202, USA.ORCID 0000-0003-1530-3242
Nikhlesh K SinghIntegrative Biosciences Center, Wayne State University, Detroit, MI 48202, USA.

Funding

VISION RESEARCH--COREP30EY004068 · NEI · WAYNE STATE UNIVERSITY · PI LINDA D HAZLETT · 1985 to 2026
$13.2M
Role of Toll-Like Receptors in Bacterial KeratitisR01EY016058 · NEI · WAYNE STATE UNIVERSITY · PI HAZLETT, LINDA D · 2005 to 2023
$6.0M
CELLULAR MECHANISMS OF PATHOLOGICAL RETINAL NEOVASCULARIZATIONR01EY029709 · NEI · WAYNE STATE UNIVERSITY · PI SINGH, NIKHLESH KUMAR · 2019 to 2023
$1.9M
NEI NIH HHS EY016058NEI NIH HHS EY029709NEI NIH HHS P30 EY004068NEI NIH HHS P30EY04068NEI NIH HHS R01 EY016058NEI NIH HHS R01 EY029709
6 · The paper itself

Abstract

Nanoscience and nanotechnology have revolutionized key areas of environmental sciences, including biological and physical sciences. Nanoscience is useful in interconnecting these sciences to find new hybrid avenues targeted at improving daily life. Pharmaceuticals, regenerative medicine, and stem cell research are among the prominent segments of biological sciences that will be improved by nanostructure innovations. The present review was written to present a comprehensive insight into various emerging nanomaterials, such as nanoparticles, nanowires, hybrid nanostructures, and nanoscaffolds, that have been useful in mice for ocular tissue engineering and regeneration. Furthermore, the current status, future perspectives, and challenges of nanotechnology in tracking cells or nanostructures in the eye and their use in modified regenerative ophthalmology mechanisms have also been proposed and discussed in detail. In the present review, various research findings on the use of nano-biomaterials in retinal regeneration and retinal remediation are presented, and these findings might be useful for future clinical applications.

Indexed as

nano-biomaterials and retinananodisksnanoparticlesnanoparticles and retinal regenerationnanoscaffolds and retinal regenerationscaffolds

Identifiers

PMID34443710
PMCPMC8399153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.