Evidence map›Paper›PMID 34443685›Full record

ArticleMolecules (Basel, Switzerland)2021

Fungal α-1,3-Glucan as a New Pathogen-Associated Molecular Pattern in the Insect Model Host

Sylwia Stączek, Agnieszka Zdybicka-Barabas, Iwona Wojda, Adrian Wiater, Paweł Mak, Piotr Suder, Krzysztof Skrzypiec, Małgorzata Cytryńska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Interactions ofInternational journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
  4. Journal of fungi (Basel, Switzerland) · 2023
    Article
  5. Review
  6. Review
  7. Frontiers in fungal biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sylwia StączekDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0002-4879-1329
Agnieszka Zdybicka-BarabasDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0003-3146-3836
Iwona WojdaDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.
Adrian WiaterDepartment of Industrial and Environmental Microbiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0003-1433-3634
Paweł MakDepartment of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7 St., 30-387 Krakow, Poland.ORCID 0000-0002-5222-3922
Piotr SuderDepartment of Analytical Chemistry and Biochemistry, Faculty of Materials Sciences and Ceramics, AGH University of Science and Technology, Mickiewicza 30 Ave., 30-059 Krakow, Poland.
Krzysztof SkrzypiecAnalytical Laboratory, Faculty of Chemistry, Maria Curie-Skłodowska University, M.C. Skłodowska Square 5, 20-031 Lublin, Poland.
Małgorzata CytryńskaDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19 St., 20-033 Lublin, Poland.ORCID 0000-0002-7621-2363
Maria Curie-Skłodowska University · PLAGH University of Krakow · PLJagiellonian University · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 16.16.160.557Narodowe Centrum Nauki 2018/31/B/NZ3/01226Narodowe Centrum Nauki UMO-2013/09/N/NZ6/00838
6 · The paper itself

Abstract

Recognition of pathogen-associated molecular patterns (PAMPs) by appropriate pattern recognition receptors (PRRs) is a key step in activating the host immune response. The role of a fungal PAMP is attributed to β-1,3-glucan. The role of α-1,3-glucan, another fungal cell wall polysaccharide, in modulating the host immune response is not clear. This work investigates the potential of α-1,3-glucan as a fungal PAMP by analyzing the humoral immune response of the greater wax moth

Indexed as

Host-Pathogen InteractionsAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesAspergillusFat BodyGene Expression RegulationGlucansHemolymphImmunizationLarvaMothsPathogen-Associated Molecular Pattern MoleculesProtein BindingSurvival Analysisalpha-1,3-glucanAnti-Infective AgentsAntimicrobial Cationic PeptidesGlucansPathogen-Associated Molecular Pattern Moleculesantimicrobial peptidesAspergillus nigerGalleria mellonellainsect immune responsepathogen-associated molecular patternpattern recognition receptorsα-1,3-glucan

Identifiers

PMID34443685
PMCPMC8399224
OpenAlexW3194708179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.