Evidence map›Paper›PMID 34443638›Full record

ReviewMolecules (Basel, Switzerland)2021

Advances in Biomimetic Nanoparticles for Targeted Cancer Therapy and Diagnosis.

Chaw Yee Beh, Ray Putra Prajnamitra, Li-Lun Chen, Patrick Ching-Ho Hsieh

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Modular functionalization of cellular nanodiscs enables targeted delivery of chemotherapeutics into tumors.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chaw Yee BehInstitute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.ORCID 0000-0003-1392-0589
Ray Putra PrajnamitraInstitute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.
Li-Lun ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.
Patrick Ching-Ho HsiehInstitute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.ORCID 0000-0002-8910-3596

Funding

Health Longevity Grand Challenge AS-HLGC-109-05Ministry of Science and Technology, Taiwan 110-2740-B-001-003, 109-2321-B-001-012The Academia Sinica Thematic Research Program AS-107-TPL12The National Health Research Institute EX109-10907SITranslational Medical Research Program AS-KPQ-110-BioMed
6 · The paper itself

Abstract

Biomimetic nanoparticles have recently emerged as a novel drug delivery platform to improve drug biocompatibility and specificity at the desired disease site, especially the tumour microenvironment. Conventional nanoparticles often encounter rapid clearance by the immune system and have poor drug-targeting effects. The rapid development of nanotechnology provides an opportunity to integrate different types of biomaterials onto the surface of nanoparticles, which enables them to mimic the natural biological features and functions of the cells. This mimicry strategy favours the escape of biomimetic nanoparticles from clearance by the immune system and reduces potential toxic side effects. Despite the rapid development in this field, not much has progressed to the clinical stage. Thus, there is an urgent need to develop biomimetic-based nanomedicine to produce a highly specific and effective drug delivery system, especially for malignant tumours, which can be used for clinical purposes. Here, the recent developments for various types of biomimetic nanoparticles are discussed, along with their applications for cancer imaging and treatments.

Indexed as

AnimalsAntineoplastic AgentsBiocompatible MaterialsBiomimetic MaterialsBiomimeticsDrug Delivery SystemsHumansNanomedicineNanoparticlesNanotechnologyNeoplasmsAntineoplastic AgentsBiocompatible Materialsactive targetingbiomimeticcancer therapyimagingimmunotherapynanoparticles

Identifiers

PMID34443638
PMCPMC8401254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.