Evidence map›Paper›PMID 34443623›Full record

ReviewMolecules (Basel, Switzerland)2021

Latest Insights on Novel Deep Eutectic Solvents (DES) for Sustainable Extraction of Phenolic Compounds from Natural Sources.

Julio Serna-Vázquez, Mohd Zamidi Ahmad, Grzegorz Boczkaj, Roberto Castro-Muñoz

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Ecofriendly Extraction of Polyphenols fromMolecules (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Extraction of Polyphenols from Slovenian Hop (Plants (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Extraction of Bioactive Compounds fromMolecules (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julio Serna-VázquezTecnologico de Monterrey, Campus Ciudad de México, Calle del Puente 222, Ejidos de Huipulco, Ciudad de México 14380, Mexico.
Mohd Zamidi AhmadOrganic Materials Innovation Center (OMIC), Department of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK.ORCID 0000-0002-8132-3818
Grzegorz BoczkajDepartment of Process Engineering and Chemical Technology, Faculty of Chemistry, Gdansk University of Technology, 11/12 Narutowicza St., 80-233 Gdansk, Poland.ORCID 0000-0002-5874-7591
Roberto Castro-MuñozDepartment of Process Engineering and Chemical Technology, Faculty of Chemistry, Gdansk University of Technology, 11/12 Narutowicza St., 80-233 Gdansk, Poland.ORCID 0000-0002-7657-3302

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenolic compounds have long been of great importance in the pharmaceutical, food, and cosmetic industries. Unfortunately, conventional extraction procedures have a high cost and are time consuming, and the solvents used can represent a safety risk for operators, consumers, and the environment. Deep eutectic solvents (DESs) are green alternatives for extraction processes, given their low or non-toxicity, biodegradability, and reusability. This review discusses the latest research (in the last two years) employing DESs for phenolic extraction, solvent components, extraction yields, extraction method characteristics, and reviewing the phenolic sources (natural products, by-products, wastes, etc.). This work also analyzes and discusses the most relevant DES-based studies for phenolic extraction from natural sources, their extraction strategies using DESs, their molecular mechanisms, and potential applications.

Indexed as

Biological ProductsDeep Eutectic SolventsPhenolsChemical FractionationGreen Chemistry TechnologySolventsBiological ProductsDeep Eutectic SolventsPhenolsSolventsbiologically active compoundsgreen solventsmedicinal plantsmicrowave-assisted extractionselective separationultrasonic-assisted extraction

Identifiers

PMID34443623
PMCPMC8401793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.