ArticleMolecules (Basel, Switzerland)2021
Smartphone-Assisted Colorimetric Detection of Glutathione and Glutathione Reductase Activity in Human Serum and Mouse Liver Using Hemin/G-Quadruplex DNAzyme.
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 23 citations in OpenAlex.
- O-Phthalaldehyde Derivatization for the Paper-Based Fluorometric Determination of Glutathione in Nutritional Supplements.Molecules (Basel, Switzerland) · 2024Article
- Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease.Nutrition & metabolism · 2024Article
- Gradient Guided-Mode Resonance Biosensor with Smartphone Readout.Biosensors · 2023Article
- Near-Field Communication Tag for Colorimetric Glutathione Determination with a Paper-Based Microfluidic Device.Biosensors · 2023Article
- Target-induced activation of DNAzyme for highly sensitive colorimetric detection of bleomycinRSC advances · 2022Article
- Superoxide Dismutase and Glutathione Reductase as Indicators of Oxidative Stress Levels May Relate to Geriatric Hip Fractures' Survival and Walking Ability: A Propensity Score Matching Study.Clinical interventions in aging · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Abnormal levels of reduced glutathione (GSH) and glutathione reductase (GR) are usually related to a variety of diseases, so it is of great significance to determine the GSH concentration and GR activity. We herein develop a smartphone-assisted colorimetric biosensor for the detection of GSH and GR activity in human serum and mouse liver using hemin/G-quadruplex DNAzyme. Firstly, an obvious color change from colorless to green can be observed, owing to the high peroxidase-like activity of hemin/G-quadruplex DNAzyme toward 2,2'-azino-bis(3-ethylbenzothiozoline-6-sulfonic acid) (ABTS). With the addition of GSH or GR, the H
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