Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 3 institutions in 1 country.
Olalla Barreiro-CostaCentro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador.
Gabriela Morales-NoboaDNA Replication and Genome Instability Unit, Grupo de Investigación en Biodiversidad, Zoonosis y Salud Pública (GIBCIZ), Instituto de Investigación en Zoonosis-CIZ, Facultad de Ciencias Químicas, Facultad de Ciencias Agrícolas, Universidad Central del Ecuador, Quito 170521, Ecuador.
Patricio Rojas-SilvaCentro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador.
Eliana Lara-BarbaDNA Replication and Genome Instability Unit, Grupo de Investigación en Biodiversidad, Zoonosis y Salud Pública (GIBCIZ), Instituto de Investigación en Zoonosis-CIZ, Facultad de Ciencias Químicas, Facultad de Ciencias Agrícolas, Universidad Central del Ecuador, Quito 170521, Ecuador.ORCID 0000-0001-5148-9959
Javier Santamaría-AguirreDNA Replication and Genome Instability Unit, Grupo de Investigación en Biodiversidad, Zoonosis y Salud Pública (GIBCIZ), Instituto de Investigación en Zoonosis-CIZ, Facultad de Ciencias Químicas, Facultad de Ciencias Agrícolas, Universidad Central del Ecuador, Quito 170521, Ecuador.ORCID 0000-0002-1683-5737
Natalia Bailón-MoscosoDepartamento de Ciencias de la Salud, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.ORCID 0000-0003-2754-1328
Juan Carlos Romero-BenavidesDepartamento de Química, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.ORCID 0000-0003-1660-1217
Ana HerreraDepartamento de Ciencias de la Salud, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.
Cristina CuevaDepartamento de Ciencias de la Salud, Universidad Técnica Particular de Loja, Loja 1101608, Ecuador.
Lenin Ron-GarridoDNA Replication and Genome Instability Unit, Grupo de Investigación en Biodiversidad, Zoonosis y Salud Pública (GIBCIZ), Instituto de Investigación en Zoonosis-CIZ, Facultad de Ciencias Químicas, Facultad de Ciencias Agrícolas, Universidad Central del Ecuador, Quito 170521, Ecuador.
Ana PovedaDNA Replication and Genome Instability Unit, Grupo de Investigación en Biodiversidad, Zoonosis y Salud Pública (GIBCIZ), Instituto de Investigación en Zoonosis-CIZ, Facultad de Ciencias Químicas, Facultad de Ciencias Agrícolas, Universidad Central del Ecuador, Quito 170521, Ecuador.ORCID 0000-0003-1505-1372
Jorge Heredia-MoyaCentro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador.ORCID 0000-0001-7620-9140
Central University of Ecuador · ECUniversidad Técnica Particular de Loja · ECUniversidad UTE · EC
Funding
Académie de Recherche et d´Enseignement Supérieur (ARES) SNCorporación Ecuatoriana para el Desarrollo de la Investigación y la Academia (CEDIA) CEPRA XI-2017-10SENPLADES 9175.0000.0000.377784 and 91750000.0000.375239Universidad Central del Ecuador Dirección General de Investigación y Proyectos-DGIP, project #6Universidad Técnica Particular de Loja PROY_INV_QUI_2017_2222Universidad UTE SN
6 · The paper itself
Abstract
This work focuses on the search and development of drugs that may become new alternatives to the commercial drugs currently available for treatment of leishmaniasis. We have designed and synthesized 12 derivatives of bis(spiropyrazolone)cyclopropanes. We then characterized their potential application in therapeutic use. For this, the in vitro biological activities against three eukaryotic models-
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Synthesis and Evaluation of Biological Activities of Bis(spiropyrazolone)cyclopropanes: A Potential Application against Leishmaniasis. · full record | OpenQuestion