Evidence map›Paper›PMID 34443474›Full record

ReviewMolecules (Basel, Switzerland)2021

Overview of the Antioxidant and Anti-Inflammatory Activities of Selected Plant Compounds and Their Metal Ions Complexes.

Paulina Mucha, Anna Skoczyńska, Magdalena Małecka, Paweł Hikisz, Elzbieta Budzisz

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 220 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. BiogenicRSC advances · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Essential Oil ofPlants (Basel, Switzerland) · 2026
    Review
  16. Article
  17. Nutraceuticals ofDrug design, development and therapy · 2026
    Review
  18. Article
  19. Review
  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Paulina MuchaDepartment of the Chemistry of Cosmetic Raw Materials, Faculty of Pharmacy, Medical University of Łódź, Muszyńskiego 1, 90-151 Łódź, Poland.
Anna SkoczyńskaDepartment of Pharmacology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Poniatowskiego 15, 41-200 Sosnowiec, Poland.
Magdalena MałeckaDepartment of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163/165, 90-236 Łódź, Poland.ORCID 0000-0003-3384-9855
Paweł HikiszDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Łódź, Poland.
Elzbieta BudziszDepartment of the Chemistry of Cosmetic Raw Materials, Faculty of Pharmacy, Medical University of Łódź, Muszyńskiego 1, 90-151 Łódź, Poland.ORCID 0000-0001-9949-8723
Medical University of Lodz · PLUniversity of Łódź · PLMedical University of Silesia · PL

Funding

Uniwersytet Łódzki B1811100000050.01Uniwersytet Medyczny w Lodzi 503/3-066- 02/503-31-001
6 · The paper itself

Abstract

Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-inflammatory, anticancer, and other beneficial effects. This review highlights the different bioactivities of flavonoids, chromones, and coumarins and their metal-ions complexes due to different structural characteristics. In addition to insight into the most studied antioxidative properties of these compounds, the first part of the review provides a comprehensive overview of exogenous and endogenous sources of reactive oxygen and nitrogen species, oxidative stress-mediated damages of lipids and proteins, and on protective roles of antioxidant defense systems, including plant-derived antioxidants. Additionally, the review covers the anti-inflammatory and antimicrobial activities of flavonoids, chromones, coumarins and their metal-ion complexes which support its application in medicine, pharmacy, and cosmetology.

Indexed as

Anti-Inflammatory AgentsAntioxidantsCoordination ComplexesFree RadicalsHumansIonsMetalsPhytochemicalsPlantsAnti-Inflammatory AgentsAntioxidantsCoordination ComplexesFree RadicalsIonsMetalsPhytochemicalsanti-inflamatory activityantioxidantcrystal structure of metal ion complexes with flavonoidsflavonoids

Identifiers

PMID34443474
PMCPMC8398118
OpenAlexW3192783508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.