Evidence map›Paper›PMID 34443421›Full record

ReviewMolecules (Basel, Switzerland)2021

Plant-Derived Pesticides as an Alternative to Pest Management and Sustainable Agricultural Production: Prospects, Applications and Challenges.

Augusto Lopes Souto, Muriel Sylvestre, Elisabeth Dantas Tölke, Josean Fechine Tavares, José Maria Barbosa-Filho, Gerardo Cebrián-Torrejón

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 1 pooled it
47.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 1 synthesis or guideline pooled it, 372 citations in OpenAlex.

  1. Frontiers in pharmacology · 2023
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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Augusto Lopes SoutoPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Universidade Federal da Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0001-8946-9953
Muriel SylvestreCOVACHIM-M2E Laboratory EA 3592, Department of Chemistry, Fouillole Campus, University of the French West Indies, UFR Sciences Exactes et Naturelles, CEDEX, 97157 Pointe-à-Pitre, France.
Elisabeth Dantas TölkeDepartamento de Botânica, Instituto de Biociências, Universidade de São Paulo, São Paulo 05508-090, Brazil.
Josean Fechine TavaresPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Universidade Federal da Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0003-0293-2605
José Maria Barbosa-FilhoPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Universidade Federal da Paraíba, João Pessoa 58051-900, Brazil.ORCID 0000-0002-9567-4096
Gerardo Cebrián-TorrejónCOVACHIM-M2E Laboratory EA 3592, Department of Chemistry, Fouillole Campus, University of the French West Indies, UFR Sciences Exactes et Naturelles, CEDEX, 97157 Pointe-à-Pitre, France.
Universidade Federal da Paraíba · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pests and diseases are responsible for most of the losses related to agricultural crops, either in the field or in storage. Moreover, due to indiscriminate use of synthetic pesticides over the years, several issues have come along, such as pest resistance and contamination of important planet sources, such as water, air and soil. Therefore, in order to improve efficiency of crop production and reduce food crisis in a sustainable manner, while preserving consumer's health, plant-derived pesticides may be a green alternative to synthetic ones. They are cheap, biodegradable, ecofriendly and act by several mechanisms of action in a more specific way, suggesting that they are less of a hazard to humans and the environment. Natural plant products with bioactivity toward insects include several classes of molecules, for example: terpenes, flavonoids, alkaloids, polyphenols, cyanogenic glucosides, quinones, amides, aldehydes, thiophenes, amino acids, saccharides and polyketides (which is not an exhaustive list of insecticidal substances). In general, those compounds have important ecological activities in nature, such as: antifeedant, attractant, nematicide, fungicide, repellent, insecticide, insect growth regulator and allelopathic agents, acting as a promising source for novel pest control agents or biopesticides. However, several factors appear to limit their commercialization. In this critical review, a compilation of plant-derived metabolites, along with their corresponding toxicology and mechanisms of action, will be approached, as well as the different strategies developed in order to meet the required commercial standards through more efficient methods.

Indexed as

AgriculturePest Control, BiologicalInsecticidesPesticidesPlantsToxins, BiologicalInsecticidesPesticidesToxins, Biologicalbio-based pesticidesbiopesticideschemical ecologynatural productspest control

Identifiers

PMID34443421
PMCPMC8400533
OpenAlexW3188360322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.