Evidence map›Paper›PMID 34443358›Full record

ArticleMolecules (Basel, Switzerland)2021

Chemical Characterization and Anti-HIV-1 Activity Assessment of Iridoids and Flavonols from

Francesca Guzzo, Rosita Russo, Cinzia Sanna, Odeta Celaj, Alessia Caredda, Angela Corona, Enzo Tramontano, Antonio Fiorentino, Francesca Esposito, Brigida D'Abrosca

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Promising inhibition of diabetes-related enzymes and antioxidant properties ofJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  4. HIV-1 Integrase Inhibition Activity by Spiroketals Derived fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Francesca GuzzoDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, DiSTABiF University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-8104-3197
Rosita RussoDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, DiSTABiF University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-2235-6302
Cinzia SannaDepartment of Life and Environmental Sciences, University of Cagliari, Via Sant'Ignazio da Laconi 13, 09123 Cagliari, Italy.ORCID 0000-0001-9797-2460
Odeta CelajDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, DiSTABiF University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.
Alessia CareddaDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, ss554, km 4500, Monserrato, 09042 Cagliari, Italy.
Angela CoronaDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, ss554, km 4500, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-6630-8636
Enzo TramontanoDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, ss554, km 4500, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0002-4849-0980
Antonio FiorentinoDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, DiSTABiF University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-9439-7074
Francesca EspositoDepartment of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, ss554, km 4500, Monserrato, 09042 Cagliari, Italy.ORCID 0000-0001-9725-7977
Brigida D'AbroscaDepartment of Environmental Biological and Pharmaceutical Sciences and Technologies, DiSTABiF University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.ORCID 0000-0002-6556-5462
University of Cagliari · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants are the everlasting source of a wide spectrum of specialized metabolites, characterized by wide variability in term of chemical structures and different biological properties such antiviral activity. In the search for novel antiviral agents against Human Immunodeficiency Virus type 1 (HIV-1) from plants, the phytochemical investigation of

Indexed as

Anti-HIV AgentsFlavonolsHIV-1IridoidsPlant ExtractsScrophulariaHIV IntegraseHIV Reverse TranscriptaseHumansMolecular StructurePlant LeavesAnti-HIV AgentsFlavonolsHIV IntegraseHIV Reverse TranscriptaseIridoidsPlant ExtractsflavonoidsHIV-1 integraseiridoidsNMRRT-associated RNase HScrophularia trifoliatastructural characterization

Identifiers

PMID34443358
PMCPMC8398805
OpenAlexW3191158560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.