Evidence map›Paper›PMID 34443327›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Antiplasmodial Activity of Bisindolylcyclobutenediones.

Duc Hoàng Lande, Abed Nasereddin, Arne Alder, Tim W Gilberger, Ron Dzikowski, Johann Grünefeld, Conrad Kunick

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Duc Hoàng LandeInstitut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethoven straße 55, 38106 Braunschweig, Germany.
Abed NasereddinDepartment of Microbiology and Molecular Genetics, IMRIC, The Kuvin Center for the Study of Infectious and Tropical Diseases, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Arne AlderCentre for Structural Systems Biology, 22607 Hamburg, Germany.ORCID 0000-0003-4918-4640
Tim W GilbergerCentre for Structural Systems Biology, 22607 Hamburg, Germany.
Ron DzikowskiDepartment of Microbiology and Molecular Genetics, IMRIC, The Kuvin Center for the Study of Infectious and Tropical Diseases, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.ORCID 0000-0001-7878-1650
Johann GrünefeldInstitut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethoven straße 55, 38106 Braunschweig, Germany.
Conrad KunickInstitut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethoven straße 55, 38106 Braunschweig, Germany.ORCID 0000-0001-7041-5322
Technische Universität Braunschweig · DEUniversität Hamburg · DE

Funding

Bundesministerium für Bildung und Forschung BMBF BioDisc 7 - 13GW0024
6 · The paper itself

Abstract

Malaria is one of the most dangerous infectious diseases. Because the causative

Indexed as

AntimalarialsMolecular Docking SimulationPlasmodium falciparumHumansMolecular StructureProtein Kinase InhibitorsProtozoan ProteinsStructure-Activity RelationshipAntimalarialsProtein Kinase InhibitorsProtozoan Proteinsbisindolylmaleimidecyclobutenedionedrug designdrug screeningFriedel-Crafts reactionglycogen synthase kinase-3indolemalariamolecular dockingplasmodium

Identifiers

PMID34443327
PMCPMC8402075
OpenAlexW3192357244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.