Evidence map›Paper›PMID 34443314›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, DFT Calculations, Antiproliferative, Bactericidal Activity and Molecular Docking of Novel Mixed-Ligand Salen/8-Hydroxyquinoline Metal Complexes.

Badriah Saad Al-Farhan, Maram T Basha, Laila H Abdel Rahman, Ahmed M M El-Saghier, Doaa Abou El-Ezz, Adel A Marzouk, Mohamed R Shehata, Ehab M Abdalla

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 52 citations in OpenAlex.

  1. NovelPharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Badriah Saad Al-FarhanChemistry Department, Faculty of Girls for Science, King Khalid University, Abha 61421, Saudi Arabia.
Maram T BashaChemistry Department, College of Science, University of Jeddah, Jeddah 21959, Saudi Arabia.ORCID 0000-0002-1416-0844
Laila H Abdel RahmanChemistry Department, Faculty of Science, Sohag University, Sohag 82534, Egypt.
Ahmed M M El-SaghierChemistry Department, Faculty of Science, Sohag University, Sohag 82534, Egypt.
Doaa Abou El-EzzPharmacology and Toxicology Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA University), Giza 12556, Egypt.
Adel A MarzoukDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt.
Mohamed R ShehataChemistry Department, Faculty of Science, Cairo University, Giza 12613, Egypt.ORCID 0000-0003-1289-0285
Ehab M AbdallaChemistry Department, Faculty of Science, New Valley University, Alkharga 72511, Egypt.ORCID 0000-0003-3456-3883
Sohag University · EGAl-Azhar University · EGCairo University · EGKing Khalid University · SAOctober University of Modern Sciences and Arts · EGSouth Valley University · EGUniversity of Jeddah · SA

Funding

Deanship of Scientific Research at King Khaled University, Abha, Saudi Arabia GRP/261/42
6 · The paper itself

Abstract

Despite the common use of salens and hydroxyquinolines as therapeutic and bioactive agents, their metal complexes are still under development. Here, we report the synthesis of novel mixed-ligand metal complexes (MSQ) comprising salen (S), derived from (2,2'-{1,2-ethanediylbis[nitrilo(E) methylylidene]}diphenol, and 8-hydroxyquinoline (Q) with Co(II), Ni(II), Cd(II), Al(III), and La(III). The structures and properties of these MSQ metal complexes were investigated using molar conductivity, melting point, FTIR,

Indexed as

Density Functional TheoryMolecular Docking SimulationAnti-Bacterial AgentsCarbon-13 Magnetic Resonance SpectroscopyCell Line, TumorCell ProliferationCoordination ComplexesEthylenediaminesHumansHydrogen-Ion ConcentrationInhibitory Concentration 50LigandsMicrobial Sensitivity TestsMolecular ConformationOxyquinolinePowder DiffractionAnti-Bacterial AgentsCoordination Complexesdisalicylaldehyde ethylenediamineEthylenediaminesLigandsOxyquinoline8-hydroxyquinolineanticancerantimicrobialmixed-ligandquantum calculationsalen

Identifiers

PMID34443314
PMCPMC8401699
OpenAlexW3187901330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.