Evidence map›Paper›PMID 34442858›Full record

ArticleMicroorganisms2021

Antimicrobial Peptide L18R Displays a Modulating Action against Inter-Kingdom Biofilms in the Lubbock Chronic Wound Biofilm Model.

Paola Di Fermo, Tecla Ciociola, Silvia Di Lodovico, Simonetta D'Ercole, Morena Petrini, Laura Giovati, Stefania Conti, Mara Di Giulio, Luigina Cellini

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Anti-Antibiotics (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Current and prospective therapeutic strategies: tacklingFrontiers in cellular and infection microbiology · 2023
    Review
  8. Article
  9. Recent Advances and Opportunities in the Study ofFrontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Paola Di FermoDepartment of Pharmacy, University "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.
Tecla CiociolaDepartment of Medicine and Surgery, University of Parma, 43125 Parma, Italy.ORCID 0000-0001-6499-2545
Silvia Di LodovicoDepartment of Pharmacy, University "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0001-9281-5028
Simonetta D'ErcoleDepartment of Medical, Oral and Biotechnological Sciences, University of "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-4797-4019
Morena PetriniDepartment of Medical, Oral and Biotechnological Sciences, University of "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-3849-4304
Laura GiovatiDepartment of Medicine and Surgery, University of Parma, 43125 Parma, Italy.ORCID 0000-0001-7514-1789
Stefania ContiDepartment of Medicine and Surgery, University of Parma, 43125 Parma, Italy.ORCID 0000-0001-9973-8352
Mara Di GiulioDepartment of Pharmacy, University "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-8375-9404
Luigina CelliniDepartment of Pharmacy, University "G. d'Annunzio" Chieti-Pescara, 66100 Chieti, Italy.
University of Chieti-Pescara · ITUniversity of Parma · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca Luigina Cellini and Mara Di Giulio FAR 2020Ministero dell'Istruzione, dell'Università e della Ricerca Research Grant PRIN 2017 SFBFER from MIUR, Italy.
6 · The paper itself

Abstract

Chronic wound infections represent an important health problem due to the reduced response to antimicrobial treatment of the pathogens organized in structured biofilms. This study investigated the effects of the previously described antifungal peptide L18R against three representative wound pathogens:

Indexed as

antimicrobial peptideCandida albicanschronic woundsconfocal laser scanning microscopyinter-kingdom biofilmLubbock chronic wound biofilm modelPseudomonas aeruginosascanning electron microscopyStaphylococcus aureus

Identifiers

PMID34442858
PMCPMC8399358
OpenAlexW3193994273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.