Evidence map›Paper›PMID 34442703›Full record

ArticleMicroorganisms2021

Antiretroviral Therapy Dampens Mucosal CD4

Alessandro Lazzaro, Giuseppe Pietro Innocenti, Letizia Santinelli, Claudia Pinacchio, Gabriella De Girolamo, Paolo Vassalini, Gianfranco Fanello, Claudio Maria Mastroianni, Giancarlo Ceccarelli, Gabriella d'Ettorre

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Alessandro LazzaroDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.
Giuseppe Pietro InnocentiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.ORCID 0000-0002-9975-9871
Letizia SantinelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.ORCID 0000-0002-5621-058X
Claudia PinacchioDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.
Gabriella De GirolamoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.
Paolo VassaliniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.
Gianfranco FanelloDepartment of Emergency Surgery-Emergency Endoscopic Unit, Sapienza University of Rome, Policlinico Umberto I, 00185 Roma, Italy.
Claudio Maria MastroianniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.ORCID 0000-0002-1286-467X
Giancarlo CeccarelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.ORCID 0000-0001-5921-3180
Gabriella d'EttorreDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Policlinico Umberto I of Rome, 00185 Roma, Italy.ORCID 0000-0002-3571-5677
Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV infection is characterized by a severe deterioration of an immune cell-mediated response due to a progressive loss of CD4

Indexed as

antiretroviral therapyARTGALTHIV-1immune activationmicrobiomemucosal immunologyTh1Th17

Identifiers

PMID34442703
PMCPMC8402205
OpenAlexW3186600967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.