Evidence map›Paper›PMID 34442624›Full record

ArticleMicroorganisms2021

Nanomotion Spectroscopy as a New Approach to Characterize Bacterial Virulence.

Maria I Villalba, Leonardo Venturelli, Ronnie Willaert, Maria E Vela, Osvaldo Yantorno, Giovanni Dietler, Giovanni Longo, Sandor Kasas

Abstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Toward a role for the acoustic field in cells interaction.Frontiers in systems neuroscience · 2025
    Article
  4. Rapid Detection ofBiomedicines · 2024
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria I VillalbaLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Leonardo VenturelliLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Ronnie WillaertResearch Group Structural Biology Brussels, Alliance Research Group VUB-UGent NanoMicrobiology (NAMI), 1050 Brussels, Belgium.ORCID 0000-0002-5400-7019
Maria E VelaInstituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Universidad Nacional de La Plata-CONICET, 1900 La Plata, Argentina.
Osvaldo YantornoCentro de Investigación y Desarrollo en Fermentaciones Industriales (CINDEFI), Facultad de Ciencias Exactas, Universidad Nacional de La Plata-CONICET, 1900 La Plata, Argentina.ORCID 0000-0002-3236-1025
Giovanni DietlerLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Giovanni LongoIstituto Di Struttura Della Materia-CNR, 00133 Roma, Italy.ORCID 0000-0003-2434-2155
Sandor KasasLaboratory of Biological Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

Funding

Agencia Nacional de Promoción Científica y Tecnológica PICT:2016-0679Agencia Nacional de Promoción Científica y Tecnológica PICT 2017-2444Consejo Nacional de Investigaciones Científicas y Técnicas PUE 22920170100100COFWO Flanders AUGE/13/19; I002620NGebert Rüf Stiftung GRS-024/14NASA NNH16ZDA001N-CLDTCHSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 200021-144321Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030L_197946Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 407240_167137Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung CRSII5_173863Swiss Government Excellence Scholarships ESKAS-Nr:2018.0647
6 · The paper itself

Abstract

Atomic force microscopy (AFM)-based nanomotion detection is a label-free technique that has been used to monitor the response of microorganisms to antibiotics in a time frame of minutes. The method consists of attaching living organisms onto an AFM cantilever and in monitoring its nanometric scale oscillations as a function of different physical-chemical stimuli. Up to now, we only used the cantilever oscillations variance signal to assess the viability of the attached organisms. In this contribution, we demonstrate that a more precise analysis of the motion pattern of the cantilever can unveil relevant medical information about bacterial phenotype. We used

Indexed as

AFMbacteriaB. pertussisnanomotion

Identifiers

PMID34442624
PMCPMC8398272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.