Evidence map›Paper›PMID 34442523›Full record

ArticleMicromachines2021

Rapid Microfluidic Mixing Method Based on Droplet Rotation Due to PDMS Deformation.

Chunyang Wei, Chengzhuang Yu, Shanshan Li, Feng Pan, Tiejun Li, Zichao Wang, Junwei Li

Abstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunyang WeiHebei Key Laboratory of Robotic Sensing and Human-Robot Interactions, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.
Chengzhuang YuState Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin 300130, China.
Shanshan LiHebei Key Laboratory of Robotic Sensing and Human-Robot Interactions, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.ORCID 0000-0001-8293-9676
Feng PanHebei Key Laboratory of Robotic Sensing and Human-Robot Interactions, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.
Tiejun LiHebei Key Laboratory of Robotic Sensing and Human-Robot Interactions, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.
Zichao WangHebei Key Laboratory of Robotic Sensing and Human-Robot Interactions, School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.
Junwei LiInstitute of Biophysics, School of Science, Hebei University of Technology, Tianjin 300401, China.ORCID 0000-0002-1724-4752

Funding

Department of Human Resources and Social Security of Hebei Province C20200314Fund for Distinguish Young Scholars in Tianjin 2018 3rd Round 180191Hebei Natural Science Foundation of China E2020202101; F2021202001Hebei Science and Technology Foundation 19271707DJiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology FMZ202016National Natural Science Foundation of China 51728502; 51505123
6 · The paper itself

Abstract

Droplet-based micromixers have shown great prospects in chemical synthesis, pharmacology, biologics, and diagnostics. When compared with the active method, passive micromixer is widely used because it relies on the droplet movement in the microchannel without extra energy, which is more concise and easier to operate. Here we present a droplet rotation-based microfluidic mixer that allows rapid mixing within individual droplets efficiently. PDMS deformation is used to construct subsidence on the roof of the microchannel, which can deviate the trajectory of droplets. Thus, the droplet shows a rotation behavior due to the non-uniform distribution of the flow field, which can introduce turbulence and induce cross-flow enhancing 3D mixing inside the droplet, achieving rapid and homogenous fluid mixing. In order to evaluate the performance of the droplet rotation-based microfluidic mixer, droplets with highly viscous fluid (60%

Indexed as

droplet rotationmicrofluidicsmixingPDMS deformation

Identifiers

PMID34442523
PMCPMC8400329

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.