Evidence map›Paper›PMID 34442437›Full record

ArticleJournal of personalized medicine2021

Risk Factors for Recanalization after Coil Embolization.

Karol Wiśniewski, Zbigniew Tyfa, Bartłomiej Tomasik, Piotr Reorowicz, Ernest J Bobeff, Bartłomiej J Posmyk, Marlena Hupało, Ludomir Stefańczyk, Krzysztof Jóźwik, Dariusz J Jaskólski

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Packing density and the angiographic results of coil embolization of intracranial aneurysms: A systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
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  8. OnyxGels (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Karol WiśniewskiDepartment of Neurosurgery and Neurooncology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.
Zbigniew TyfaInstitute of Turbomachinery, Medical Apparatus Division, Lodz University of Technology, Wolczanska 219/223, 90-924 Lodz, Poland.
Bartłomiej TomasikDepartment of Biostatistics and Translational Medicine, Medical University of Lodz, 15 Mazowiecka St., 92-215 Lodz, Poland.ORCID 0000-0001-5648-345X
Piotr ReorowiczInstitute of Turbomachinery, Medical Apparatus Division, Lodz University of Technology, Wolczanska 219/223, 90-924 Lodz, Poland.ORCID 0000-0003-0585-0488
Ernest J BobeffDepartment of Neurosurgery and Neurooncology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.ORCID 0000-0003-1891-3791
Bartłomiej J PosmykDepartment of Neurosurgery and Neurooncology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.
Marlena HupałoDepartment of Neurosurgery and Neurooncology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.
Ludomir StefańczykDepartment of Radiology-Diagnostic Imaging, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.
Krzysztof JóźwikInstitute of Turbomachinery, Medical Apparatus Division, Lodz University of Technology, Wolczanska 219/223, 90-924 Lodz, Poland.
Dariusz J JaskólskiDepartment of Neurosurgery and Neurooncology, Medical University of Lodz, Kopcińskiego 22, 90-153 Lodz, Poland.ORCID 0000-0002-9971-9677
Medical University of Lodz · PLLodz University of Technology · PLHarvard University · US

Funding

Medical University of Lodz (statutory activities) 503-11-001-19-00Narodowe Centrum Badań i Rozwoju LIDER/12/0056/L-10/18/NCBR/2019
6 · The paper itself

Abstract

The aim of our study was to identify risk factors for recanalization 6 months after coil embolization using clinical data followed by computational fluid dynamics (CFD) analysis.

methodsFirstly, clinical data of 184 patients treated with coil embolization were analyzed retrospectively. Secondly, aneurysm models for high/low recanalization risk were generated based on ROC curves and their cut-off points. Afterward, CFD was utilized to validate the results.

resultsIn multivariable analysis, aneurysm filling during the first embolization was an independent risk factor whilst packing density was a protective factor of recanalization after 6 months in patients with aSAH. For patients with unruptured aneurysms, packing density was found to be a protective factor whilst the aneurysm neck size was an independent risk factor. Complex flow pattern and multiple vortices were associated with aneurysm shape and were characteristic of the high recanalization risk group.

conclusionsStatistical analysis suggested that there are various factors influencing recanalization risk. Once certain values of morphometric parameters are exceeded, a complex flow with numerous vortices occurs. This phenomenon was revealed due to CFD investigations that validated our statistical research. Thus, the complex flow pattern itself can be treated as a relevant recanalization predictor.

Indexed as

coilscomplex flow patternscomputational fluid dynamicsembolizationflow diverterspredictorsrecanalization

Identifiers

PMID34442437
PMCPMC8398571
OpenAlexW3194567754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.