Evidence map›Paper›PMID 34442411›Full record

ArticleJournal of personalized medicine2021

Expression of PD-L1 Is Associated with Inflammatory Microenvironment in Surgical Specimens of Non-Small Cell Lung Cancer.

Ivan Simundza, Dragan Krnic, Josko Juricic, Benjamin Benzon, Rina Simundza, Ivan Mario Stanicic, Vesna Capkun, Katarina Vukojevic, Merica Glavina Durdov

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ivan SimundzaDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.
Dragan KrnicDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.ORCID 0000-0003-1493-339X
Josko JuricicDepartment of Surgery, University Hospital of Split, 21000 Split, Croatia.
Benjamin BenzonDepartment of Anatomy, Histology and Embryology, School of Medicine, University of Split, 21000 Split, Croatia.
Rina SimundzaDepartment of Gynaecology, University Hospital of Split, 21000 Split, Croatia.
Ivan Mario StanicicDepartment of Pathology, University Hospital of Split, 21000 Split, Croatia.
Vesna CapkunDepartment of Anatomy, Histology and Embryology, School of Medicine, University of Split, 21000 Split, Croatia.
Katarina VukojevicDepartment of Anatomy, Histology and Embryology, School of Medicine, University of Split, 21000 Split, Croatia.ORCID 0000-0003-2182-2890
Merica Glavina DurdovDepartment of Pathology, University Hospital of Split, 21000 Split, Croatia.
University of Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to analyse the expression of PD-L1 in non-small cell lung cancer (NSCLC) and its correlation with immune microenvironment response (IMR), clinic-pathological parameters, and outcome. The sample included 76 male and 32 female patients who underwent surgical resection. The mean age of the males was 66 years, and that of the females was 64 years. Adenocarcinoma (ADC) was diagnosed in 68 (63%) cases, squamous cell carcinoma in 35 (32%) cases, and NSCLC (not otherwise specified) in 5 (5%) cases. Metastatic lymph nodes were found in 38 (36%) patients, 18 with N1 nodes and 20 with N2 nodes. PD-L1 expression was valuated as the percentage of positive cancer cells among all cancer cells. Gender, age, and histologic type were not associated with PD-L1 expression (all

Indexed as

immunotherapylung surgeryNSCLCoverall survivalPD-L1

Identifiers

PMID34442411
PMCPMC8398962
OpenAlexW3188712557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.