Evidence map›Paper›PMID 34442406›Full record

ArticleJournal of personalized medicine2021

Impact of Pneumococcal Urinary Antigen Testing in COVID-19 Patients: Outcomes from the San Matteo COVID-19 Registry (SMACORE).

Pietro Valsecchi, Marta Colaneri, Valentina Zuccaro, Erika Asperges, Filippo Costanzo, Bianca Mariani, Silvia Roda, Rita Minucci, Francesco Bertuccio, Elia Fraolini and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Pietro ValsecchiDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Marta ColaneriDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Valentina ZuccaroDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Erika AspergesDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-1618-8867
Filippo CostanzoDivision of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Bianca MarianiUnit of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-1508-8776
Silvia RodaDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Rita MinucciFaculty of Medicine, University of Pavia, 27100 Pavia, Italy.
Francesco BertuccioDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Elia FraoliniDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Matteo BosioDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Claudio TirelliDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.ORCID 0000-0002-4502-9902
Tiberio OggionniDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Angelo CorsicoDivision of Chest Medicine, IRCCS Policlinico San Matteo Foundation, 27100 Pavia, Italy.
Raffaele BrunoDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-0235-9207
Policlinico San Matteo Fondazione · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite low rates of bacterial co-infections, most COVID-19 patients receive antibiotic therapy. We hypothesized that patients with positive pneumococcal urinary antigens (PUAs) would benefit from antibiotic therapy in terms of clinical outcomes (death, ICU admission, and length of stay). The San Matteo COVID-19 Registry (SMACORE) prospectively enrolls patients admitted for COVID-19 pneumonia at IRCCS Policlinico San Matteo, Pavia. We retrospectively extracted the data of patients tested for PUA from October to December 2020. Demographic, clinical, and laboratory data were recorded. Of 469 patients, 42 tested positive for PUA (8.95%), while 427 (91.05%) tested negative. A positive PUA result had no significant impact on death (HR 0.53 CI [0.22-1.28]

Indexed as

antibiotic therapyCOVID-19pneumococcal urinary antigenSARS-CoV-2Streptococcus pneumoniae

Identifiers

PMID34442406
PMCPMC8401143
OpenAlexW3191211383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.