ArticleJournal of personalized medicine2021
The Metabolic Score for Insulin Resistance (METS-IR) as a Predictor of Incident Ischemic Heart Disease: A Longitudinal Study among Korean without Diabetes.
Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
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Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Metabolic score for insulin resistance and the incidence of cardiovascular disease: a meta-analysis of cohort studies.Frontiers in endocrinology · 2025Pooled it
- Sex-specific association between metabolic score for insulin resistance and mortality in incident peritoneal dialysis patients.Renal failure · 2026Article
- Impaired adipogenesis and lipid storage capacity in subcutaneous adipose tissue of patients with PMOS.JCI insight · 2026Article
- A novel score to evaluate nonlinear association between insulin resistance and new-onset diabetes mellitus: A cohort analysis.Medicine · 2026Article
- Association of METS-IR with breast cancer risk: a large-scale retrospective cohort study of Korean women.BMC public health · 2026Article
- Age-related changes in METS-IR and HOMA-IR in obese adults and their relationship with cardiometabolic comorbidities.Archives of endocrinology and metabolism · 2026Article
- Joint effects and dynamic trajectories of metabolic insulin resistance and systemic inflammation in the risk of renal cell carcinoma: a UK Biobank cohort analysis.World journal of urology · 2026Article
- From Metabolism to Mind: The Cardio-Metabolic-Brain Axis and the Role of Insulin Resistance-A Review.Biomedicines · 2026Review
- The Prognostic Significance of the Metabolic Score for Insulin Resistance and Subclinical Myocardial Injury for Cardiovascular Mortality in the General Population.Journal of clinical medicine · 2026Article
- Exploring the gut microbiome in type 2 diabetes across different insulin resistance levels: a machine learning approach.Frontiers in nutrition · 2026Article
- Metabolic score for insulin resistance is associated with metabolic dysfunction-associated steatotic liver disease among adults with hypertension: a cross-sectional secondary analysis of a Chinese single-center health check-up population.Frontiers in endocrinology · 2026Article
- Article
- Assessing the Discriminative Power of Metabolic Indices for PMOS Detection in Normal-Weight Women.International journal of women's health · 2026Article
- The Prognostic Value of Insulin Resistance Indices for Major Adverse Cardiovascular Events in Young and Middle-Aged Patients With Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Beyond HOMA-IR: Comparative Evaluation of Insulin Resistance and Anthropometric Indices Across Prediabetes and Type 2 Diabetes Mellitus in Metabolic Syndrome Patients.Life (Basel, Switzerland) · 2025Article
- Inverse Association Between METS-IR and Lung Cancer Risk: The Role of BMI in a Nationwide Korean Cohort.Cancers · 2025Article
- Which insulin resistance indices best predict future frailty progression in a cardiovascular-kidney-metabolic syndrome stage 0-3 population: a national prospective cohort and machine learning study.Diabetology & metabolic syndrome · 2025Article
- The association between baseline and long-term status of metabolic score for insulin resistance index and the incidence of cardiometabolic multimorbidity.BMC public health · 2025Article
- The association of the metabolic score for insulin resistance and metabolic dysfunction-related steatosis liver disease: a population-based observational study.European journal of medical research · 2025Observational
- Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolic score for insulin resistance (METS-IR) is a novel noninsulin-based marker for assessing the risk of insulin resistance and cardiometabolic risk. However, whether METS-IR is associated with incident ischemic heart disease (IHD) risk is not well known. Therefore, we aimed to investigate the longitudinal effect of METS-IR on incident IHD risk in a large cohort of Korean adults without diabetes. Data were assessed from 17,943 participants without diabetes from the Health Risk Assessment Study (HERAS) and Korea Health Insurance Review and Assessment (HIRA) data. The participants were divided into four groups according to METS-IR index quartiles: (ln ((2 × fasting plasma glucose) + triglyceride) × body mass index)/(ln (HDL-cholesterol)). We prospectively assessed hazard ratios (HRs) with 95% confidence intervals (CIs) for IHD using multivariate Cox proportional hazard regression models over a 50-month period. During the follow-up period, 332 participants (1.9%) developed IHD. HRs of IHD for METS-IR quartiles 1-4 were 1.00, were 1.62 (95% CI 1.04-2.53), 1.87 (95% CI 1.20-2.91), and 2.11 (95% CI 1.35-3.30), respectively, after adjusting for potential confounding variables. A higher METS-IR precedes future IHD among Koreans without diabetes. Moreover, compared with metabolic syndrome, METS-IR had a better predictive value for IHD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.