Evidence map›Paper›PMID 34442384›Full record

ArticleJournal of personalized medicine2021

Ethnic Disparities in the Development of Sight-Threatening Diabetic Retinopathy in a UK Multi-Ethnic Population with Diabetes: An Observational Cohort Study.

Manjula D Nugawela, Sarega Gurudas, A Toby Prevost, Rohini Mathur, John Robson, Wasim Hanif, Azeem Majeed, Sobha Sivaprasad

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Age-Related Macular Degeneration and Diabetic Retinopathy.Journal of personalized medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Manjula D NugawelaUCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK.ORCID 0000-0001-5989-9530
Sarega GurudasUCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK.
A Toby PrevostDepartment of Population Health Sciences, King's College London, London WC2R 2LS, UK.
Rohini MathurLondon School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
John RobsonInstitute of Population Health Sciences, Queen Mary University of London, London E1 4NS, UK.
Wasim HanifBirmingham City School of Nursing and Midwifery, Westbourne Road, Birmingham B15 3TN, UK.
Azeem MajeedSchool of Public Health, Imperial College London, London SW7 2AZ, UK.
Sobha SivaprasadUCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK.ORCID 0000-0001-8952-0659
University College London · GBBirmingham City University · GBImperial College London · GBKing's College London · GBMoorfields Eye Hospital NHS Foundation Trust · GBQueen Mary University of London · GBUniversity of London · GB

Funding

Global Challenges Research Fund MR/P207881/1Medical Research Council MR/P027881/1Sir Henry Wellcome Postdoctoral fellowship 201375/Z/16/ZWellcome Trust 201375/Z/16/Z
6 · The paper itself

Abstract

There is little data on ethnic differences in incidence of DR and sight threatening DR (STDR) in the United Kingdom. We aimed to determine ethnic differences in the development of DR and STDR and to identify risk factors of DR and STDR in people with incident or prevalent type II diabetes (T2DM). We used electronic primary care medical records of people registered with 134 general practices in East London during the period from January 2007-January 2017. There were 58,216 people with T2DM eligible to be included in the study. Among people with newly diagnosed T2DM, Indian, Pakistani and African ethnic groups showed an increased risk of DR with Africans having highest risk of STDR compared to White ethnic groups (HR: 1.36 95% CI 1.02-1.83). Among those with prevalent T2DM, Indian, Pakistani, Bangladeshi and Caribbean ethnic groups showed increased risk of DR and STDR with Indian having the highest risk of any DR (HR: 1.24 95% CI 1.16-1.32) and STDR (HR: 1.38 95% CI 1.17-1.63) compared with Whites after adjusting for all covariates considered. It is important to optimise prevention, screening and treatment options in these ethnic minority groups to avoid health inequalities in diabetes eye care.

Indexed as

ethnicitygeneral practiceretinopathyrisk factorstype 2 diabetes

Identifiers

PMID34442384
PMCPMC8400788
OpenAlexW3186757330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.