Evidence map›Paper›PMID 34442381›Full record

ArticleJournal of personalized medicine2021

Association of

Shobana John, Karuppiah Balakrishnan, Chonlaphat Sukasem, Tharmarajan Chinnathambi Vijay Anand, Bhutorn Canyuk, Sutthiporn Pattharachayakul

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Association of decreased CYP2C9 function,Frontiers in pharmacology · 2026
    Article
  3. Review
  4. Article
  5. Frontiers in pharmacology · 2024
    Article
  6. Pharmacogenetics to Avoid Adverse Drug Reactions.Journal of personalized medicine · 2022
    Article
  7. Review
  8. Distribution ofFrontiers in pharmacology · 2022
    Article
  9. Evolution ofFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Shobana JohnDepartment of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Hat Yai 90110, Thailand.
Karuppiah BalakrishnanDepartment of Immunology, School of Biological Sciences, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India.
Chonlaphat SukasemDivision of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0003-0033-5321
Tharmarajan Chinnathambi Vijay AnandDepartment of Neurology, Meenakshi Mission Hospital and Research Center, Madurai 625107, Tamil Nadu, India.
Bhutorn CanyukDepartment of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Hat Yai 90110, Thailand.
Sutthiporn PattharachayakulDepartment of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla, Hat Yai 90110, Thailand.
Prince of Songkla University · THMadurai Kamaraj University · INMahidol University · THMeenakshi Mission Hospital and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenytoin (PHT) is one of the most commonly reported aromatic anti-epileptic drugs (AEDs) to cause cutaneous adverse reactions (CADRs), particularly severe cutaneous adverse reactions (SCARs). Although human leukocyte antigen

Indexed as

anti-epileptic drugs (AEDS)cutaneous adverse drug reactions (CADRs)CYP2C9*3genetic risk factorsHLA BIndiaphenytoin (PHT)South India

Identifiers

PMID34442381
PMCPMC8400937
OpenAlexW3185339676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.