Evidence map›Paper›PMID 34442368›Full record

ReviewJournal of personalized medicine2021

Electronic Cigarettes and Asthma: What Do We Know So Far?

Serafeim-Chrysovalantis Kotoulas, Paraskevi Katsaounou, Renata Riha, Ioanna Grigoriou, Despoina Papakosta, Dionysios Spyratos, Konstantinos Porpodis, Kalliopi Domvri, Athanasia Pataka

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  7. Longitudinal Association Between Exclusive and Dual Use of Cigarettes and Electronic Nicotine Delivery Systems and Asthma Among U.S. Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
    Article
  8. Article
  9. Article
  10. Asthma and Tobacco Smoking.Journal of personalized medicine · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Serafeim-Chrysovalantis KotoulasClinic of Respiratory Failure, General Hospital of Thessaloniki Georgios Papanikolaou, Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.ORCID 0000-0002-6092-1341
Paraskevi Katsaounou1st ICU "Evangelismos Hospital", School of Medicine, National and Kapodistrian University of Athens, Ypsilantou 45-47, 10676 Athens, Greece.ORCID 0000-0002-8736-619X
Renata RihaSleep Research Unit, Department of Sleep Medicine, The University of Edinburgh, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.ORCID 0000-0001-8983-9985
Ioanna GrigoriouClinic of Respiratory Failure, General Hospital of Thessaloniki Georgios Papanikolaou, Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.
Despoina PapakostaDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.
Dionysios SpyratosDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.
Konstantinos PorpodisDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.ORCID 0000-0001-7215-2191
Kalliopi DomvriDepartment of Pulmonary Medicine, General Hospital of Thessaloniki "Georgios Papanikolaou", Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.
Athanasia PatakaClinic of Respiratory Failure, General Hospital of Thessaloniki Georgios Papanikolaou, Aristotle University of Thessaloniki, Leoforos Papanikolaou, 57010 Thessaloniki, Greece.ORCID 0000-0002-3252-6694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic cigarettes (EC) are a novel product, marketed as an alternative to tobacco cigarette. Its effects on human health have not been investigated widely yet, especially in specific populations such as patients with asthma. With this review, we use the existing literature in order to answer four crucial questions concerning: (1) ECs' role in the pathogenesis of asthma; (2) ECs' effects on lung function and airway inflammation in patients with asthma; (3) ECs' effects on asthma clinical characteristics in asthmatics who use it regularly; and (4) ECs' effectiveness as a smoking cessation tool in these patients. Evidence suggests that many EC compounds might contribute to the pathogenesis of asthma. Lung function seems to deteriorate by the use of EC in this population, while airway inflammation alters, with the aggravation of T-helper-type-2 (Th2) inflammation being the most prominent but not the exclusive effect. EC also seems to worsen asthma symptoms and the rate and severity of exacerbations in asthmatics who are current vapers, whilst evidence suggests that its effectiveness as a smoking cessation tool might be limited. Asthmatic patients should avoid using EC.

Indexed as

airway inflammationasthmaasthma controlasthma pathogenesiselectronic cigarettelung functionreviewsmoking cessation

Identifiers

PMID34442368
PMCPMC8399607

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.