ArticleJournal of personalized medicine2021
Pre-Metabolic Syndrome and Incidence of Type 2 Diabetes and Hypertension: From the Korean Genome and Epidemiology Study.
Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Clinical sub-phenotypes of co-occurring metabolic syndrome and pre-frailty and their associated factors in older adults: findings from Whitehall II study.Frontiers in medicine · 2026Article
- The Predictive Ability and Trend of Continuous Metabolic Syndrome (cMets) Score as a Marker for the Presence of Metabolic Syndrome among Iranian Adults from 2007 to 2025 Using STEPS Studies.International journal of preventive medicine · 2026Article
- Effect of a Phytochemical-Rich Olive-Derived Extract on Anthropometric, Hematological, and Metabolic Parameters.Nutrients · 2024Article
- Article
- Shapely additive values can effectively visualize pertinent covariates in machine learning when predicting hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Independent association between age- and sex-specific metabolic syndrome severity score and cardiovascular disease and mortality.Scientific reports · 2023Article
- Development and validation of a continuous metabolic syndrome severity score in the Tehran Lipid and Glucose Study.Scientific reports · 2023Article
- Association between Lower-to-Upper Ratio of Appendicular Skeletal Muscle and Metabolic Syndrome.Journal of clinical medicine · 2022Article
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Authors and funding
3 authors.
Funding
Abstract
The aim of this study was to investigate the prevalence of premetabolic syndrome (pre-MetSyn) and its components and to longitudinally examine their association with new-onset type 2 diabetes (T2D) or hypertension. A total of 4037 men and 4400 women aged 40 to 69 years were selected from the Korean Genome and Epidemiology Study, observed from 2001 to 2014. Pre-MetSyn was defined as the presence of one or two components of MetSyn (B, elevated blood pressure; G, elevated glucose; H, low HDL-cholesterol; T, elevated triglycerides; W, increased waist circumference). The prevalence of pre-MetSyn was higher than that of non-MetSyn and MetSyn in both men and women. In multivariate Cox regression analyses, G, T, G+T, W+G, B+G, B+T, W+T, B+H, and H+T in men and G, T, G+H, B+T, and H+T in women were significantly associated with new-onset T2D. B, W, B+H, B+T, W+H, and W+T in men and B, B+T, B+H, B+W, and W+H in women were significantly associated with new-onset hypertension. The prevalence of pre-MetSyn components and their associations with new-onset T2D or hypertension differed according to sex and disease. Our results suggest that specific phenotypes of pre-MetSyn may be important factors for predicting and preventing the development of T2D and hypertension.
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