Evidence map›Paper›PMID 34442033›Full record

ArticleJournal of clinical medicine2021

High-Resolution

Jens M Debacker, Vanessa Schelfhout, Lieve Brochez, David Creytens, Yves D'Asseler, Philippe Deron, Vincent Keereman, Koen Van de Vijver, Christian Vanhove, Wouter Huvenne

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05068687 (Peroperative Assessment of Tumour Resection Margins Using High-resolution 18F-FDG-PET/CT in Malignancies of the Head and Neck, a Pilot Study), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05068687 nacompletednot on this map

Peroperative Assessment of Tumour Resection Margins Using High-resolution 18F-FDG-PET/CT in Malignancies of the Head and Neck, a Pilot Study

TypeinterventionalSponsorUniversity Hospital, GhentRan2020 to 2022Enrolled9ConditionsHead and Neck Neoplasms, Thyroid Neoplasm, Skin NeoplasmArmshigh-resolution PET-CT specimen imaging.
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Towards molecular imaging-guided intervention theatres in oncology.European journal of nuclear medicine and molecular imaging · 2024
    Article
  7. Review
  8. Article
  9. Direct co-registration of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. Highlights of the 34th EANM Annual Congress 2021, 2nd virtual edition: "FROM HAMBURG WITH LOVE".European journal of nuclear medicine and molecular imaging · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jens M DebackerDepartment of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-8293-2885
Vanessa SchelfhoutCancer Research Institute Ghent, 9000 Ghent, Belgium.
Lieve BrochezDepartment of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0001-6105-6719
David CreytensCancer Research Institute Ghent, 9000 Ghent, Belgium.ORCID 0000-0002-6064-1673
Yves D'AsselerCancer Research Institute Ghent, 9000 Ghent, Belgium.
Philippe DeronDepartment of Head and Skin, Ghent University, 9000 Ghent, Belgium.
Vincent KeeremanDepartment of Electronics and Information Systems, Ghent University, 9000 Ghent, Belgium.
Koen Van de VijverCancer Research Institute Ghent, 9000 Ghent, Belgium.ORCID 0000-0002-2026-9790
Christian VanhoveCancer Research Institute Ghent, 9000 Ghent, Belgium.ORCID 0000-0002-3988-5980
Wouter HuvenneDepartment of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-0567-8983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surgical treatment of head and neck malignancies relies on the complete removal of tumoral tissue, while inadequate margins necessitate the use of adjuvant therapy. However, most positive margins are identified postoperatively as deep margins, and intraoperative identification of the deep positive margins could help achieve adequate surgical margins and decrease adjuvant therapies. To improve deep-margin identification, we investigated whether the use of high-resolution preclinical PET and CT could increase certainty about the surgical margins in three dimensions. Patients with a malignancy of the head and neck planned for surgical resection were administered a clinical activity of 4MBq/kg

Indexed as

deep marginshead and neck cancermargin assessmentmolecular imagingPET/CT

Identifiers

PMID34442033
PMCPMC8397229

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.