Evidence map›Paper›PMID 34441949›Full record

ReviewJournal of clinical medicine2021

The Relative Merits of Posterior Surgical Treatments for Multi-Level Degenerative Cervical Myelopathy Remain Uncertain: Findings from a Systematic Review.

Xiaoyu Yang, Aref-Ali Gharooni, Rana S Dhillon, Edward Goacher, Edward W Dyson, Oliver Mowforth, Alexandru Budu, Guy Wynne-Jones, Jibin Francis, Rikin Trivedi and 16 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
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  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 18 institutions in 5 countries.

Xiaoyu YangDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.ORCID 0000-0002-9055-1230
Aref-Ali GharooniDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.
Rana S DhillonDepartment of Neurosurgery, St Vincent's Hospital Melbourne, Melbourne, VIC 3065, Australia.
Edward GoacherDepartment of Neurosurgery, Royal Hallamshire Hospital, Sheffield S10 2JF, UK.ORCID 0000-0002-2621-8388
Edward W DysonVictor Horsley Department of Neurosurgery, National Hospital for Neurology & Neurosurgery, London WC1N 3BG, UK.
Oliver MowforthDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.ORCID 0000-0001-6788-745X
Alexandru BuduDepartment of Neurosurgery, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield S10 2JF, UK.ORCID 0000-0001-6783-6943
Guy Wynne-JonesDepartment of Orthopaedics, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK.
Jibin FrancisDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.
Rikin TrivediDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.
Marcel IvanovDepartment of Neurosurgery, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield S10 2JF, UK.
Sashin AhujaWelsh Centre for Spinal Surgery & Trauma, University hospital of Wales, Cardiff CF14 4XW, UK.ORCID 0000-0001-8676-6100
Kia RezajooiSpinal Surgery Unit, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, UK.
Andreas K DemetriadesEdinburgh Spinal Surgery Outcome Studies Group, Department of Neurosurgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.
David ChoiDepartment of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London Hospitals, London WC1N 3BG, UK.
Antony H BatemanRoyal Derby Spinal Centre, Royal Derby Hospital, Derby DE22 3NE, UK.ORCID 0000-0002-5093-7243
Nasir QuraishiNottingham Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals, Nottingham NG7 2UH, UK.
Vishal KumarDepartment of Orthopaedics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India.
Manjul TripathiDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India.ORCID 0000-0002-5679-3439
Sandeep MohindraDepartment of Neurosurgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India.ORCID 0000-0002-4629-4900
Erlick A PereiraNeurosciences Research Centre, Institute of Molecular and Clinical Sciences, St George's, University of London, London WC1E 7HU, UK.
Giles CritchleyBrighton and Sussex Medical School, South East Neurosurgery and South East Spinal Surgery, University Hospitals Sussex NHS Foundation Trust, Brighton BN1 9PX, UK.
Michael G FehlingsDivision of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, ON M5T 2S8, Canada.ORCID 0000-0002-5722-6364
Peter J A HutchinsonDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.
Benjamin M DaviesDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.ORCID 0000-0003-0591-5069
Mark R N KotterDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB0 0GG, UK.ORCID 0000-0001-5145-7199
University of Cambridge · GBPost Graduate Institute of Medical Education and Research · INNational Health Service · GBBrighton and Sussex Medical School · GBEdinburgh Royal Infirmary · GBLeiden University · NLNational Hospital for Neurology and Neurosurgery · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBNottingham University Hospitals NHS Trust · GBRoyal Derby Hospital · GBRoyal Hallamshire Hospital · GBRoyal London Hospital · GBRoyal National Orthopaedic Hospital · GBSt George's, University of London · GBSt Vincent's Hospital Melbourne · AUUniversity Health Network · CAUniversity Hospital of Wales · GBWellcome/MRC Cambridge Stem Cell Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the reporting of study design and characteristics in multi-level degenerative cervical myelopathy (DCM) treated by posterior surgical approaches, and perform a comparison of clinical and radiographic outcomes between different approaches.

methodsA literature search was performed in Embase and MEDLINE between 1995-2019 using a sensitive search string combination. Studies were selected by predefined selection criteria: Full text articles in English, with >10 patients (prospective) or >50 patients (retrospective), reporting outcomes of multi-level DCM treated by posterior surgical approach.

resultsA total of 75 studies involving 19,510 patients, conducted worldwide, were identified. Laminoplasty was described in 56 studies (75%), followed by laminectomy with (36%) and without fusion (16%). The majority of studies were conducted in Asia (84%), in the period of 2016-2019 (51%), of which laminoplasty was studied predominantly. Twelve (16%) prospective studies and 63 (84%) retrospective studies were identified. The vast majority of studies were conducted in a single centre (95%) with clear inclusion/exclusion criteria and explicit cause of DCM. Eleven studies (15%) included patients with ossification of the posterior longitudinal ligament exclusively with cohorts of 57 to 252. The clinical and radiographic outcomes were reported with heterogeneity when comparing laminoplasty, laminectomy with and without fusion.

conclusionsHeterogeneity in the reporting of study and sample characteristics exists, as well as in clinical and radiographic outcomes, with a paucity of studies with a higher level of evidence. Future studies are needed to elucidate the clinical effectiveness of posterior surgical treatments.

Indexed as

cervical spinedegenerative cervical myelopathyfusionlaminectomylaminoplastymulti-levelmyelopathy

Identifiers

PMID34441949
PMCPMC8397218
OpenAlexW3193501306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.