Evidence map›Paper›PMID 34441919›Full record

ArticleJournal of clinical medicine2021

Severe Myocardial Dysfunction after Non-Ischemic Cardiac Arrest: Effectiveness of Percutaneous Assist Devices.

Stéphane Manzo-Silberman, Christoph Nix, Andreas Goetzenich, Pierre Demondion, Chantal Kang, Michel Bonneau, Alain Cohen-Solal, Pascal Leprince, Guillaume Lebreton

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Stéphane Manzo-SilbermanDepartment of Cardiology, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Denis Diderot University, INSERM UMRS 942, 75010 Paris, France.ORCID 0000-0002-0703-1331
Christoph NixAbiomed Europe GmbH, Neuenhofer Weg 3, D-52074 Aachen, Germany.
Andreas GoetzenichAbiomed Europe GmbH, Neuenhofer Weg 3, D-52074 Aachen, Germany.
Pierre DemondionDepartment of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
Chantal KangXP-MED, 78100 Saint Germain en Laye, France.
Michel BonneauXP-MED, 78100 Saint Germain en Laye, France.
Alain Cohen-SolalDepartment of Cardiology, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Denis Diderot University, INSERM UMRS 942, 75010 Paris, France.
Pascal LeprinceDepartment of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
Guillaume LebretonDepartment of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
Sorbonne Université · FRAbiomed (Germany) · DEInserm · FRInstitut du Porc · FR

Funding

ABIOMED unrestricted
6 · The paper itself

Abstract

introductionDespite the improvements in standardized cardiopulmonary resuscitation, survival remains low, mainly due to initial myocardial dysfunction and hemodynamic instability. Our goal was to compare the efficacy of two left ventricular assist devices on resuscitation and hemodynamic supply in a porcine model of ventricular fibrillation (VF) cardiac arrest.

methodsSeventeen anaesthetized pigs had 12 min of untreated VF followed by 6 min of chest compression and boluses of epinephrine. Next, a first defibrillation was attempted and pigs were randomized to any of the three groups: control (

resultsOnly one of 5 pigs in the control group, 5 of 5 pigs in the Impella group, and 5 of 7 pigs in the ECMO group had ROSC (

conclusionEarly mechanical circulatory support appeared to improve resuscitation rates in a shockable rhythm model of cardiac arrest. This approach appears promising and should be further evaluated.

Indexed as

acute heart failurecardiogenic shockextracorporeal membrane oxygenationleft ventricular assist devicemechanical circulatory supportorgan replacement therapiesphysiopathology

Identifiers

PMID34441919
PMCPMC8396996
OpenAlexW3194099349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.