Evidence map›Paper›PMID 34441884›Full record

ArticleJournal of clinical medicine2021

Quadratus Lumborum Block Reduces Postoperative Opioid Consumption and Decreases Persistent Postoperative Pain Severity in Patients Undergoing Both Open and Laparoscopic Nephrectomies-A Randomized Controlled Trial.

Michał Borys, Patrycja Szajowska, Mariusz Jednakiewicz, Grzegorz Wita, Tomasz Czarnik, Marcin Mieszkowski, Bułat Tuyakov, Piotr Gałkin, Mansur Rahnama-Hezavah, Mirosław Czuczwar and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05860309 (Preoperative Versus Postoperative Ultrasound Guided Quadratous Lunborum Block for Postoperative Analgesia Following Open Nephrectomy, Acomparative Study), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05860309 nacompletednot on this mapstarted 2023, after this paper: background citation

Preoperative Versus Postoperative Ultrasound Guided Quadratous Lunborum Block for Postoperative Analgesia Following Open Nephrectomy, Acomparative Study

TypeinterventionalSponsorAin Shams UniversityRan2023 to 2025Enrolled100ConditionsRegional Blocks, Renal SurgeryArmsquadratous lumborum block
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michał BorysSecond Department of Anesthesia and Intensive Care, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-6183-811X
Patrycja SzajowskaDepartment of Anesthesia and Intensive Care, Frederic Chopin Clinical Provincial Hospital No. 1, 35-310 Rzeszów, Poland.
Mariusz JednakiewiczDepartment of Anesthesia and Intensive Care, Frederic Chopin Clinical Provincial Hospital No. 1, 35-310 Rzeszów, Poland.
Grzegorz WitaDepartment of Anesthesia and Intensive Care, Frederic Chopin Clinical Provincial Hospital No. 1, 35-310 Rzeszów, Poland.
Tomasz CzarnikDepartment of Anesthesiology, Intensive Care and Regional ECMO Center, Institute of Medical Sciences, Opole University, 45-040 Opole, Poland.
Marcin MieszkowskiDepartment of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, 10-719 Olsztyn, Poland.ORCID 0000-0002-8753-4958
Bułat TuyakovDepartment of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, 10-719 Olsztyn, Poland.
Piotr GałkinDepartment of Anesthesia and Intensive Care, Jedrzej Sniadecki Hospital, 15-027 Białystok, Poland.
Mansur Rahnama-HezavahChair and Department of Dental Surgery, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-5622-7330
Mirosław CzuczwarSecond Department of Anesthesia and Intensive Care, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-9025-6717
Paweł PiwowarczykSecond Department of Anesthesia and Intensive Care, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-8529-484X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew regional techniques can improve pain management after nephrectomy.

methodsThis study was a randomized controlled trial conducted at two teaching hospitals. Patients undergoing elective open and laparoscopic nephrectomy were eligible to participate in the trial. A total of 100 patients were divided into a quadratus lumborum block (QLB) group (50 patients) and a control (CON) group (50 patients). At the end of surgery, but while still under general anesthesia, unilateral QLB with ropivacaine was performed on the side of nephrectomy for patients in the QLB group. The main measured outcome of this study was oxycodone consumption via a patient-controlled anesthesia (PCA) pump during the first 24 h following surgery; other measured outcomes included postoperative pain intensity assessment, patient satisfaction with pain management, and persistent pain evaluation.

resultsPatients undergoing QLB needed less oxycodone than those in the CON group (34.5 mg (interquartile range 23 to 40 mg) vs. 47.5 mg (35-50 mg);

conclusionsQLB reduces oxycodone consumption in patients undergoing open and laparoscopic nephrectomy and decreases persistent pain severity months after hospital discharge.

Indexed as

nephrectomyneuropathic pain symptom inventorypatient-controlled analgesiapersistent postoperative painquadratus lumborum block

Identifiers

PMID34441884
PMCPMC8396843

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.