Evidence map›Paper›PMID 34441845›Full record

ArticleJournal of clinical medicine2021

Effect of COVID-19 Lockdown in Spain on Structural and Functional Outcomes of Neovascular AMD Patients.

Alicia Valverde-Megías, Daniela Rego-Lorca, José Ignacio Fernández-Vigo, Antonio Murciano-Cespedosa, Alicia Megías-Fresno, Julián García-Feijoo

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Research Advances in Age-Related Macular Degeneration.Journal of clinical medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alicia Valverde-MegíasDepartment of Ophthalmology, San Carlos Clinical Hospital, 28040 Madrid, Spain.ORCID 0000-0002-6166-114X
Daniela Rego-LorcaDepartment of Ophthalmology, San Carlos Clinical Hospital, 28040 Madrid, Spain.
José Ignacio Fernández-VigoDepartment of Ophthalmology, San Carlos Clinical Hospital, 28040 Madrid, Spain.ORCID 0000-0001-8745-3464
Antonio Murciano-CespedosaDepartment of Biomathematics, Faculty of Biology, Complutense University, 28040 Madrid, Spain.
Alicia Megías-FresnoDepartment of Biochemistry and Molecular Biology, Faculty of Biology, Complutense University, 28040 Madrid, Spain.
Julián García-FeijooDepartment of Ophthalmology, San Carlos Clinical Hospital, 28040 Madrid, Spain.
Hospital Clínico San Carlos · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a retrospective single-center study of patients with neovascular age-related macular degeneration whose follow-up was delayed due to COVID-19 pandemic with at least three months between visits in Madrid, Spain. The purpose of the study was to evaluate best corrected visual acuity (BCVA) changes and try to identify features in optical coherence tomography (OCT) that could be related to more profound visual loss. It included 270 eyes. The two last visits before lockdown were used for comparison with the visit after lockdown. BCVA changed from 60.2 ± 18.2 to 55.9 ± 20.5 ETDRS letters. 29% of the eyes lost more than 5 letters. OCT was active in 67% of eyes before lockdown and in 80.4% after lockdown. Multiple lineal analysis showed that patients whose OCT before lockdown presented with a combination of intra and subretinal fluid were more likely to suffer a greater visual loss (

Indexed as

anti-VEGFCOVID-19nAMD

Identifiers

PMID34441845
PMCPMC8397186
OpenAlexW3189413200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.