Evidence map›Paper›PMID 34441826›Full record

ArticleJournal of clinical medicine2021

De Novo Cancer Incidence after Kidney Transplantation in South Korea from 2002 to 2017.

Boyeon Kim, Minjin Kang, Yoonjung Kim, Hyung Soon Lee, Banseok Kim, Jung Jun Lee, Yongjung Park, Kyung-A Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Boyeon KimDepartment of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang-si 10444, Korea.
Minjin KangResearch Institute, National Health Insurance Service Ilsan Hospital, Goyang 10444, Korea.
Yoonjung KimDepartment of Laboratory Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.
Hyung Soon LeeDepartment of Surgery, National Health Insurance Service Ilsan Hospital, Goyang 10444, Korea.ORCID 0000-0001-9825-8648
Banseok KimDepartment of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang-si 10444, Korea.ORCID 0000-0003-4888-774X
Jung Jun LeeDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.
Yongjung ParkDepartment of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang-si 10444, Korea.ORCID 0000-0001-5668-4120
Kyung-A LeeDepartment of Laboratory Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.
Yonsei University · KRNational Health Insurance Service Ilsan Hospital · KR

Funding

National Health Insurance Service Ilsan Hospital 2019-20-002
6 · The paper itself

Abstract

Advances in patient care and immunosuppressive drugs have improved graft survival, resulting in an increase in kidney transplantation (KT); however, persistent immunosuppression is thought to cause late occurrence of cancer. This population-based study consisted of a total of 14,842 patients whose data from the years 2002 to 2017 were collected from the National Health Information Database in South Korea. Malignancies occurred in 7.6% of the total KT patients. Prostate and thyroid cancers were the most common in males and females, respectively. From the age-adjusted incidence analysis, Kaposi's sarcoma showed the highest standardized incidence ratio in both male and female patients. According to the linear regression model, cancer incidence in KT recipients under immunosuppressive conditions increased by approximately 0.1% each month. Patients' age over 39 and the use of prednisolone as an initial steroid regimen were associated with increased risk of cancer development after KT. Our regression and proportional hazards models will help clinicians to predict the approximate cancer incidence risk when monitoring KT recipients. Based on the largest available national database, screening or monitoring methods for cancer detection and prevention can be established for KT patients by considering the factors involved in cancer development.

Indexed as

cancer riskkidney transplantationmalignancypopulation-based study

Identifiers

PMID34441826
PMCPMC8396914
OpenAlexW3192270932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.