Evidence map›Paper›PMID 34441565›Full record

ArticleFoods (Basel, Switzerland)2021

White Button Mushroom Extracts Modulate Hepatic Fibrosis Progression, Inflammation, and Oxidative Stress In Vitro and in

Paloma Gallego, Amparo Luque-Sierra, Gonzalo Falcon, Pilar Carbonero, Lourdes Grande, Juan D Bautista, Franz Martín, José A Del Campo

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Ergothioneine-rich water extracts ofFrontiers in nutrition · 2026
    Article
  3. Evaluation of Immunoprotective Activities of White Button Mushroom (Animals : an open access journal from MDPI · 2025
    Article
  4. Chitosan andToxicology research · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paloma GallegoUnit for Clinical Management of Digestive Diseases and CIBERehd, Valme University Hospital, 41014 Seville, Spain.
Amparo Luque-SierraAndalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), University of Pablo de Olavide-University of Sevilla-CSIC, 41013 Seville, Spain.ORCID 0000-0002-9090-3048
Gonzalo FalconDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Sevilla, 41012 Seville, Spain.
Pilar CarboneroDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Sevilla, 41012 Seville, Spain.
Lourdes GrandeUnit for Clinical Management of Digestive Diseases and CIBERehd, Valme University Hospital, 41014 Seville, Spain.
Juan D BautistaDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, University of Sevilla, 41012 Seville, Spain.
Franz MartínAndalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), University of Pablo de Olavide-University of Sevilla-CSIC, 41013 Seville, Spain.
José A Del CampoUnit for Clinical Management of Digestive Diseases and CIBERehd, Valme University Hospital, 41014 Seville, Spain.ORCID 0000-0002-6037-1028

Funding

Instituto de Salud Carlos III PI14-01349Junta de Andalucía PAI-BIO311Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL2017-86927-R
6 · The paper itself

Abstract

Liver fibrosis can be caused by non-alcoholic steatohepatitis (NASH), among other conditions. We performed a study to analyze the effects of a nontoxic, water-soluble extract of the edible mushroom

Indexed as

atherosclerosishepatic fibrosishigh-fat dietinflammationmushroom extractoxidative stress

Identifiers

PMID34441565
PMCPMC8392037

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.