Evidence map›Paper›PMID 34441519›Full record

ArticleFoods (Basel, Switzerland)2021

A Response Surface Methodology (RSM) Approach for Optimizing the Attenuation of Human IgE-Reactivity to β-Lactoglobulin (β-Lg) by Hydrostatic High Pressure Processing.

Xin Sun, Jialing Vivien Chua, Quynh Anh Le, Francisco J Trujillo, Mi-Hwa Oh, Dianne E Campbell, Sam Mehr, Nanju Alice Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin SunSchool of Chemical Engineering, University of New South Wales, Syndey, NSW 2052, Australia.
Jialing Vivien ChuaSchool of Chemical Engineering, University of New South Wales, Syndey, NSW 2052, Australia.
Quynh Anh LeSchool of Chemical Engineering, University of New South Wales, Syndey, NSW 2052, Australia.
Francisco J TrujilloSchool of Chemical Engineering, University of New South Wales, Syndey, NSW 2052, Australia.
Mi-Hwa OhNational Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.
Dianne E CampbellImmunology and Allergy, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Sam MehrImmunology and Allergy, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Nanju Alice LeeSchool of Chemical Engineering, University of New South Wales, Syndey, NSW 2052, Australia.ORCID 0000-0002-1476-0727

Funding

Rural Development Administration (Republic of Korea) PJ00932903
6 · The paper itself

Abstract

The response surface methodology (RSM) and central composite design (CCD) technique were used to optimize the three key process parameters (i.e., pressure, temperature and holding time) of the high-hydrostatic-pressure (HHP) processing either standalone or combined with moderate thermal processing to modulate molecular structures of β-lactoglobulin (β-Lg) and α-lactalbumin (α-La) with reduced human IgE-reactivity. The RSM model derived for HHP-induced molecular changes of β-Lg determined immunochemically showed that temperature (temp), pressure (p

Indexed as

high hydrostatic pressure processinghuman IgE-bindingrabbit IgG bindingresponse surface modelsα-lactalbuminβ-lactoglobulin

Identifiers

PMID34441519
PMCPMC8394912

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.