Evidence map›Paper›PMID 34441449›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Stability of OCT and OCTA in the Intensive Therapy Unit Setting.

Ella F Courtie, Aditya U Kale, Benjamin T K Hui, Xiaoxuan Liu, Nicholas I Capewell, Jonathan R B Bishop, Tony Whitehouse, Tonny Veenith, Ann Logan, Alastair K Denniston and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ella F CourtieNeuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Aditya U KaleOphthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Benjamin T K HuiOphthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Xiaoxuan LiuOphthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Nicholas I CapewellOphthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Jonathan R B BishopNIHR Surgical Reconstruction and Microbiology Research Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Tony WhitehouseCritical Care Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Tonny VeenithCritical Care Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Ann LoganAxolotl Consulting Ltd., Worcestershire, Droitwich WR9 0JS, UK.ORCID 0000-0003-3215-5042
Alastair K DennistonOphthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Richard J BlanchNeuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-6142-3280
University Hospitals Birmingham NHS Foundation Trust · GBUniversity of Warwick · GB

Funding

Medical Research Council MC_PC_19005National Institute for Health Research Surgical Reconstruction and Microbiology Research Centre 1001123
6 · The paper itself

Abstract

To assess the stability of retinal structure and blood flow measures over time and in different clinical settings using portable optical coherence tomography angiography (OCTA) as a potential biomarker of central perfusion in critical illness, 18 oesophagectomy patients completed retinal structure and blood flow measurements by portable OCT and OCTA in the eye clinic and intensive therapy unit (ITU) across three timepoints: (1) pre-operation in a clinic setting; (2) 24-48 h post-operation during ITU admission; and (3) seven days post-operation, if the patient was still admitted. Blood flow and macular structural measures were stable between the examination settings, with no consistent variation between pre- and post-operation scans, while retinal nerve fibre layer thickness increased in the post-operative scans (+2.31 µm,

Indexed as

critical careoptical coherence tomography angiographystability

Identifiers

PMID34441449
PMCPMC8394026
OpenAlexW3193720738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.