Evidence map›Paper›PMID 34441387›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review.

Vera Panzarella, Alessia Bartolone, Vito Rodolico, Giorgia Capocasale, Laura Maniscalco, Domenica Matranga, Olga Di Fede, Giuseppina Campisi

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Noninvasive Imaging Techniques as Modern Diagnostic Tools in Desquamative Gingivitis: Focus on RCM, OCT, and LC-OCT.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vera PanzarellaDepartment of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-6339-6020
Alessia BartoloneDepartment of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.
Vito RodolicoDepartment ProMISE, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-1409-4207
Giorgia CapocasaleSection of Dentistry and Maxillofacial Surgery, Department of Surgical Sciences, Paediatrics and Gynecology, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-8578-8041
Laura ManiscalcoDepartment of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7974-3963
Domenica MatrangaDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-2466-937X
Olga Di FedeDepartment of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-5562-7420
Giuseppina CampisiDepartment of Surgical, Oncological and Oral Sciences, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-9443-0495

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, presence of acantholytic cells in the blister) and by mucous membrane pemphigoid (i.e., subepithelial multilocular blister, presence of inflammatory infiltrate), but not by oral lichen planus. These patterns could offer an attractive diagnostic OCT framework to support the clinical preliminary assessment and monitoring of these complex pathological conditions.

Indexed as

desquamative gingivitisoptical coherence tomographyoral mucous membrane pemphigoidoral pemphigus vulgaris

Identifiers

PMID34441387
PMCPMC8394405

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.