Evidence map›Paper›PMID 34441332›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Colon Tissues Classification and Localization in Whole Slide Images Using Deep Learning.

Pushpanjali Gupta, Yenlin Huang, Prasan Kumar Sahoo, Jeng-Fu You, Sum-Fu Chiang, Djeane Debora Onthoni, Yih-Jong Chern, Kuo-Yu Chao, Jy-Ming Chiang, Chien-Yuh Yeh and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Choroidal imaging biomarkers as predictors of recurrent central serous chorioretinopathy: A multicenter retrospective study - MICRoN report number five.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pushpanjali GuptaDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0002-6077-9701
Yenlin HuangCollege of Medicine, Chang Gung University, Guishan 33302, Taiwan.
Prasan Kumar SahooDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0003-3496-1195
Jeng-Fu YouDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Sum-Fu ChiangDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.ORCID 0000-0001-8753-0239
Djeane Debora OnthoniDepartment of Computer Science and Information Engineering, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0001-6990-9456
Yih-Jong ChernDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Kuo-Yu ChaoCollege of Nursing, Chang Gung University of Science and Technology, Guishan 33302, Taiwan.ORCID 0000-0002-2971-8468
Jy-Ming ChiangDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Chien-Yuh YehDivision of Colon and Rectal Surgery, Chang Gung Memorial Hospital, Linkou 33305, Taiwan.
Wen-Sy TsaiCollege of Medicine, Chang Gung University, Guishan 33302, Taiwan.ORCID 0000-0001-6873-2863

Funding

MINISTRY OF SCIENCE AND TECHNOLOGY (MOST), TAIWAN 109-2221-E-182-014
6 · The paper itself

Abstract

Colorectal cancer is one of the leading causes of cancer-related death worldwide. The early diagnosis of colon cancer not only reduces mortality but also reduces the burden related to the treatment strategies such as chemotherapy and/or radiotherapy. However, when the microscopic examination of the suspected colon tissue sample is carried out, it becomes a tedious and time-consuming job for the pathologists to find the abnormality in the tissue. In addition, there may be interobserver variability that might lead to conflict in the final diagnosis. As a result, there is a crucial need of developing an intelligent automated method that can learn from the patterns themselves and assist the pathologist in making a faster, accurate, and consistent decision for determining the normal and abnormal region in the colorectal tissues. Moreover, the intelligent method should be able to localize the abnormal region in the whole slide image (WSI), which will make it easier for the pathologists to focus on only the region of interest making the task of tissue examination faster and lesser time-consuming. As a result, artificial intelligence (AI)-based classification and localization models are proposed for determining and localizing the abnormal regions in WSI. The proposed models achieved F-score of 0.97, area under curve (AUC) 0.97 with pretrained Inception-v3 model, and F-score of 0.99 and AUC 0.99 with customized Inception-ResNet-v2 Type 5 (IR-v2 Type 5) model.

Indexed as

classificationcolon cancerconvolutional neural networksdeep learninglocalizationprimary tumortransfer learning

Identifiers

PMID34441332
PMCPMC8394415

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.