ReviewDiagnostics (Basel, Switzerland)2021
Thyroid Nodule Characterization: How to Assess the Malignancy Risk. Update of the Literature.
Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05734326 (Role of US Elastography Compared With FNAC in Diagnosis of Solitary Thyroid Nodule), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of US Elastography Compared With FNAC in Diagnosis of Solitary Thyroid Nodule
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Thyroid and renal cancers: A bidirectional association.Frontiers in oncology · 2022Pooled it
- US-Elastography With Different Techniques for Thyroid Nodule Characterization: Systematic Review and Meta-analysis.Frontiers in oncology · 2022Pooled it
- TEM-Net: A Tri-Channel Edge-Aware Multi-Scale Network for Thyroid Nodule Segmentation in Ultrasound Images.Bioengineering (Basel, Switzerland) · 2026Article
- Machine learning-based classification of papillary thyroid carcinoma versus multinodular goiter using preoperative laboratory and cytology data.BMC endocrine disorders · 2026Article
- Appropriateness of Thyroid Nodule Cancer Risk Assessment and Management Recommendations Provided by Large Language Models.Journal of imaging informatics in medicine · 2025Article
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- Investigating the Applicability of the McGill Thyroid Nodule Score (MTNS) in Patients Undergoing Surgery for Thyroid Nodules: A Comparison Between Patients with and Without Papillary Thyroid Cancer.Journal of clinical practice and research · 2024Article
- A Multi-View Deep Learning Model for Thyroid Nodules Detection and Characterization in Ultrasound Imaging.Bioengineering (Basel, Switzerland) · 2024Article
- The progress of radiomics in thyroid nodules.Frontiers in oncology · 2023Review
- Nomogram incorporating preoperative clinical and ultrasound indicators to predict aggressiveness of solitary papillary thyroid carcinoma.Frontiers in oncology · 2023Article
- Editorial: Differential diagnoses of thyroid neoplasms: Molecular and histological features and the impact on follow-up.Frontiers in oncology · 2023Article
- Combined Shear Wave Elastography and EU TIRADS in Differentiating Malignant and Benign Thyroid Nodules.Cancers · 2022Article
- The Italian Consensus for the Classification and Reporting of Thyroid Cytology: Cytohistologic and molecular correlations on 37,371 nodules from a single institution.Cancer cytopathology · 2022Article
- Article
- Is Melanoma Progression Affected by Thyroid Diseases?International journal of molecular sciences · 2022Review
- Review
- Article
- Contrast-Enhanced Ultrasound: An Effective Method for Noninvasive Diagnosis of Mummified Thyroid Nodules.International journal of endocrinology · 2022Article
- Differentiation of Thyroid Nodules (C-TIRADS 4) by Combining Contrast-Enhanced Ultrasound Diagnosis Model With Chinese Thyroid Imaging Reporting and Data System.Frontiers in oncology · 2022Article
- Reconceptualize tall-cell variant papillary thyroid microcarcinoma: From a "sonographic histology" perspective.Frontiers in endocrinology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ultrasound (US) is the first imaging modality for thyroid parenchyma evaluation. In the last decades, the role of ultrasound has been improved with the introduction of new US software, such as contrast-enhanced ultrasound (CEUS) and US-elastography (USE). USE is nowadays recognized as an essential part of the multiparametric ultrasound (MPUS) examination, in particular for the indeterminate thyroid nodule with possible fine-needle aspiration cytology (FNAC) number reduction; even if further and larger studies are needed to validate it. More controversial is the role of CEUS in thyroid evaluation, due to its high variability in sensitivity and specificity. Semi-automatic US systems based on the computer-aided diagnosis (CAD) system are producing interesting results, especially as an aid to less experienced operators. New knowledge on the molecular mechanisms involved in thyroid cancer is allowing practitioners to identify new genomic thyroid markers that could reduce the number of "diagnostic" thyroidectomies. We have therefore drawn up an updated representation of the current evidence in the literature for thyroid nodule multiparametric ultrasound (MPUS) evaluation with particular regard to USE, the US CAD system and CEUS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.