Evidence map›Paper›PMID 34441304›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Clinical Characteristics and Outcome of Patients with Suspected COVID-19 in Emergency Department (RESILIENCY Study II).

Alessandro Russo, Elio Gentilini Cacciola, Cristian Borrazzo, Valeria Filippi, Tommaso Bucci, Francesco Vullo, Luigi Celani, Erica Binetti, Luigi Battistini, Giancarlo Ceccarelli and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alessandro RussoDepartment of Medical and Surgical Sciences, Infectious and Tropical Disease Unit, "Magna Graecia" University of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-3846-4620
Elio Gentilini CacciolaPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Cristian BorrazzoPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-2346-898X
Valeria FilippiPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Tommaso BucciDepartment of General Surgery, Surgical Specialties and Organ Transplantation "Paride Stefanini", Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-2895-6234
Francesco VulloDepartment of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, 00185 Rome, Italy.
Luigi CelaniPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Erica BinettiPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Luigi BattistiniPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Giancarlo CeccarelliPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0001-5921-3180
Maria AlessandroniMedical Emergency Unit, Sapienza University of Rome, Policlinico Umberto I, 00185 Rome, Italy.
Gioacchino GalardoMedical Emergency Unit, Sapienza University of Rome, Policlinico Umberto I, 00185 Rome, Italy.
Claudio Maria MastroianniPoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-1286-467X
Gabriella d'EttorrePoliclinico "Umberto I", Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-3571-5677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCOVID-19 may show no peculiar signs and symptoms that may differentiate it from other infective or non-infective etiologies; thus, early recognition and prompt management are crucial to improve survival. The aim of this study was to describe clinical, laboratory, and radiological characteristics and outcomes of hospitalized COVID-19 patients compared to those with other infective or non-infective etiologies.

methodsWe performed a prospective study from March 2020 to February 2021. All patients hospitalized for suspected or confirmed COVID-19 were prospectively recruited. All patients were evaluated according to a predefined protocol for diagnosis of suspected SARS-CoV-2 infection. The primary endpoint was evaluation of clinical, laboratory, and radiological characteristics associated or not with COVID-19 etiology at time of hospitalization in an emergency department.

resultsA total of 1036 patients were included in the study: 717 (69%) patients with confirmed COVID-19 and 319 (31%) without COVID-19, hospitalized for other causes. The main causes of hospitalization among non-COVID-19 patients were acute heart failure (44%) and bacterial pneumonia (45.8%). Overall, 30-day mortality was 9% among the COVID-19 group and 35% in the non-COVID-19 group. Multivariate analysis showed variables (fever > 3 days, dry cough, acute dyspnea, lymphocytes < 1000 × 10

conclusionsPatients with confirmed diagnosis of COVID-19 may show peculiar characteristics at time of hospitalization that could help physicians to distinguish from other infective or non-infective etiologies. Finally, a different 30-day mortality rate was observed during different periods of the pandemic.

Indexed as

acute respiratory failureCOVID-19decision treefevermortalitySARS-CoV-2

Identifiers

PMID34441304
PMCPMC8393530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.