Evidence map›Paper›PMID 34441289›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Evaluation of Hepatitis C Virus Core Antigen Assay in a Resource-Limited Setting in Pakistan.

Adeel Abid, Murad Uddin, Taj Muhammad, Safia Awan, Tanya Applegate, Gregory J Dore, Gavin Cloherty, Saeed Hamid

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. The Abbott Pandemic Defense Coalition: a unique multisector approach adds to global pandemic preparedness efforts.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adeel AbidDepartment of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.ORCID 0000-0002-0791-9226
Murad UddinDepartment of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.
Taj MuhammadDepartment of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.
Safia AwanDepartment of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.
Tanya ApplegateKirby Institute, Viral Hepatitis Clinical Research Program, UNSW Sydney, Sydney, NSW 2052, Australia.
Gregory J DoreKirby Institute, Viral Hepatitis Clinical Research Program, UNSW Sydney, Sydney, NSW 2052, Australia.
Gavin ClohertyAbbott Diagnostics, Abbott Park, IL 60064-3500, USA.
Saeed HamidDepartment of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan.

Funding

Gilead Sciences IN-PK-987-5509
6 · The paper itself

Abstract

The diagnosis of Hepatitis C virus (HCV) infection can be challenging due to its cost and a lack of access to centralized testing. There is an urgent need to develop simplified HCV testing algorithms. The aim of this study was to evaluate the performance characteristics of a Hepatitis C core antigen (HCVcAg) assay in a decentralized, resource-limited setting. This is a descriptive cross-sectional study from a highly endemic area of Karachi, Pakistan. Between October 2019 and July 2020, subjects aged 12 years and above who screened positive for HCV antibodies were simultaneously tested for HCV RNA (Xpert HCV Viral Load, GeneXpert

Indexed as

dededecentralizedGeneXpert® IVHCV Core antigenHepatitis C

Identifiers

PMID34441289
PMCPMC8394911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.