Evidence map›Paper›PMID 34441285›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Evaluation of Gait Pattern and Lower Extremity Kinematics of Children with Morquio Syndrome (MPS IV).

Jose J Salazar-Torres, Chris Church, Thomas Shields, M Wade Shrader, Lydia Fisher, William G Mackenzie, W G Stuart Mackenzie

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Natural History of Morquio A Syndrome.Journal of inherited metabolic disease · 2026
    Review
  2. Article
  3. Bone Growth Induction in Mucopolysaccharidosis IVA Mouse.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jose J Salazar-TorresNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.ORCID 0000-0003-0919-7359
Chris ChurchNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.
Thomas ShieldsNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.
M Wade ShraderNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.
Lydia FisherNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.
William G MackenzieNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.
W G Stuart MackenzieNemours A.I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morquio syndrome (mucopolysaccharidosis IV/MPS IV) is a genetic disorder leading to skeletal abnormalities and gait deviations. Research on the gait patterns and lower extremity physical characteristics associated with skeletal dysplasia in children with MPS IV is currently limited. This research aimed to provide baseline gait patterns and lower limb skeletal alignment of children with MPS IV utilizing three-dimensional instrumented gait analysis. This Institutional Review Board-approved retrospective study evaluates the kinematics of the lower extremities of children with MPS IV during gait, comparing them with an age-matched group of typically developing children. Thirty-three children with MPS IV were included (8.6 ± 4.0 years old). Children with MPS IV walk with increased anterior pelvic tilt, knee valgus, knee flexion, external tibial torsion, and reduced walking speed and stride length (

Indexed as

childrengait patternsMorquio syndromemucopolysaccharidosis IVskeletal abnormalityskeletal dysplasia

Identifiers

PMID34441285
PMCPMC8394369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.