Evidence map›Paper›PMID 34441277›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Serum Peptide Immunoglobulin G Autoantibody Response in Patients with Different Central Nervous System Inflammatory Demyelinating Disorders.

Hye Lim Lee, Jin-Woo Park, Jin Myoung Seok, Mi Young Jeon, Hojin Kim, Young-Min Lim, Ha Young Shin, Sa-Yoon Kang, Oh-Hyun Kwon, Sang-Soo Lee and 5 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hye Lim LeeDepartment of Neurology, Korea University College of Medicine, Seoul 02841, Korea.
Jin-Woo ParkDepartment of Neurology, Korea University College of Medicine, Seoul 02841, Korea.ORCID 0000-0001-5548-3378
Jin Myoung SeokDepartment of Neurology, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Korea.
Mi Young JeonSamsung Research Institute of Future Medicine, Seoul 06351, Korea.
Hojin KimDepartment of Neurology, National Cancer Center, Goyang 10408, Korea.
Young-Min LimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.ORCID 0000-0001-5074-812X
Ha Young ShinDepartment of Neurology, Yonsei University College of Medicine, Seoul 03722, Korea.
Sa-Yoon KangDepartment of Neurology, College of Medicine, Cheju National University, Cheju 63241, Korea.
Oh-Hyun KwonDepartment of Neurology, Eulji University College of Medicine, Seoul 01830, Korea.
Sang-Soo LeeDepartment of Neurology, Chungbuk National University College of Medicine, Cheongju 28644, Korea.
Hung Youl SeokDepartment of Neurology, Keimyung University School of Medicine, Daegu 41931, Korea.
Ju-Hong MinDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Sung-Hyun LeeDepartment of Neurology, Chungbuk National University College of Medicine, Cheongju 28644, Korea.
Byung-Jo KimDepartment of Neurology, Korea University College of Medicine, Seoul 02841, Korea.ORCID 0000-0002-0445-7185
Byoung Joon KimDepartment of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.

Funding

Korean Disease Control and Prevention Agency 2020-ER6901-01
6 · The paper itself

Abstract

Previous efforts to discover new surrogate markers for the central nervous system (CNS) inflammatory demyelinating disorders have shown inconsistent results; moreover, supporting evidence is scarce. The present study investigated the IgG autoantibody responses to various viral and autoantibodies-related peptides proposed to be related to CNS inflammatory demyelinating disorders using the peptide microarray method. We customized a peptide microarray containing more than 2440 immobilized peptides representing human and viral autoantigens. Using this, we tested the sera of patients with neuromyelitis optica spectrum disorders (NMOSD seropositive,

Indexed as

CNS inflammatory demyelinating disorderIgG responsepeptide microarray

Identifiers

PMID34441277
PMCPMC8392162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.