Evidence map›Paper›PMID 34441272›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The Incremental Prognostic Value of E/(e'×s') Ratio in Non-ST-Segment Elevated Acute Coronary Syndrome.

Ioana Ionac, Mihai-Andrei Lazăr, Daniel Miron Brie, Constantin Erimescu, Radu Vînă, Cristian Mornoş

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioana IonacCardiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-4516-3765
Mihai-Andrei LazărCardiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Daniel Miron BrieCardiology Department, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania.
Constantin ErimescuCardiology Department, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania.
Radu VînăViami Software, Viami Solution SRL, 011334 Bucharest, Romania.
Cristian MornoşCardiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-6096-9601

Funding

Romanian Academy of Medical Sciences and European Regional Development Fund Funding Contract 2/Axa 1/31.07.2017/SMIS 107124
6 · The paper itself

Abstract

It has been shown that the E/(e'×s') index, which associates a marker of diastolic function (E/e', early transmitral/diastolic mitral annulus velocity ratio) and a parameter that explores LV systolic performance (s', systolic mitral annulus velocity), is a good predictor of outcome in acute anterior myocardial infarction. There are no studies that have investigated the prognostic value of E/(e'×s') in a non-ST-segment elevated acute coronary syndrome (NSTE-ACS) population. Echocardiography was performed in 307 consecutive hospitalized patients with NSTE-ACS and succesful percutaneous coronary intervention, before discharge and six weeks after. The primary endpoint consisted of cardiac death or readmission due to re-infarction or heart failure. During the follow-up period (25.4 ± 3 months), cardiac events occurred in 106 patients (34.5%). Receiver operating characteristic (ROC) analysis identified E/(e'×s') at discharge as the best independent predictor of composite outcome. The optimal cut-off value was 1.63 (74% sensitivity, 67% specificity). By multivariate Cox regression analysis, E/(e'×s') was the only independent predictor of cardiac events. Kaplan-Meier analysis identified that patients with an initial E/(e'×s') > 1.63 that worsened after six weeks presented the worst prognosis regarding composite outcome, readmission, and cardiac death (all

Indexed as

cardiac eventsmitral annulus velocitiesnon-ST-segment elevated acute coronary syndromeprognostictissue Doppler imaging

Identifiers

PMID34441272
PMCPMC8394451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.