Evidence map›Paper›PMID 34441271›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The Morphological and Dynamic Changes of Ultrasound in the Evaluation of Effects of Oral Steroids Treatment for Patients with Carpal Tunnel Syndrome.

Yun-Chain Yau, Chun-Pai Yang, Ching-Po Lin, I-Ju Tsai, Ching-Mao Chang, Cheng-Chia Yang, Po-Hsuan Shih, Yin-Yin Liao

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun-Chain YauDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Chun-Pai YangDepartment of Neurology, Kuang Tien General Hospital, Taichung 433, Taiwan.
Ching-Po LinDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
I-Ju TsaiDepartment of Medical Research, Kuang Tien General Hospital, Taichung 433, Taiwan.ORCID 0000-0001-7688-3012
Ching-Mao ChangCenter for Traditional Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-3853-2067
Cheng-Chia YangDepartment of Healthcare Administration, Asia University, Taichung 413, Taiwan.ORCID 0000-0003-0579-7015
Po-Hsuan ShihInstitute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yin-Yin LiaoDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 402, Taiwan.

Funding

Ministry of Science and Technology, Taiwan MOST 109-2221-E-040 -007
6 · The paper itself

Abstract

The role of oral steroids in carpal tunnel syndrome (CTS) remains elusive. This study aims to depict the ultrasound findings and conceivable mechanisms in relation to the efficacy of oral steroids for patients with CTS by measuring the morphological and motion changes in the median nerve. In this study, CTS patients were randomized to the oral steroid group (14 participants and 22 wrists) or nicergoline group (22 participants and 35 wrists) for 4 weeks. Both treatment arms were given global symptom score (GSS) measurements and completed an ultra-sound at baseline and at 2- and 4-weeks post-treatment. In the nerve conduction study (NCS), distal motor latency (DML) was used to assess the treatment response at baseline and 4 weeks post-treatment. The cross-sectional area (CSA) and amplitude (AMP) evaluated by the maximum lateral sliding displacement represented the morphological and dynamic changes in the median nerve, respectively. The results showed that AMP, CSA, GSS, and DML were significantly im-proved in the steroid group, as compared to the nicergoline group at weeks 2 and 4 (

Indexed as

amplitudecarpal tunnel syndromecross-sectional areasteroidultrasound

Identifiers

PMID34441271
PMCPMC8391183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.