ArticleDiagnostics (Basel, Switzerland)2021
Microbiome of Saliva and Plaque in Children According to Age and Dental Caries Experience.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06575335 (Antibacterial Efficacy of Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies in Differently Abled Children- A Randomized Clinical Trial), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Antibacterial Efficacy of Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies in Differently Abled Children- A Randomized Clinical Trial
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Associations between the oral microbiome, age, and cumulative dental caries experience: a cross-sectional study.Clinical oral investigations · 2026Article
- Modulating Oral Microbiota to Prevent Dental Caries: A Microbial Ecology Approach.Dentistry journal · 2026Review
- The Oral-Gut-Brain Axis in Pediatric Populations: The Implications of Oral Dysbiosis for Systemic Inflammation and Neuroinflammation.Nutrients · 2026Review
- Predictors of Dental Caries Increment in Schoolchildren: A Longitudinal Study of Salivary and Behavioral Risk Factors.Dentistry journal · 2026Article
- A cross-sectional study of supragingival microbiome depending on age in Korean population.Scientific reports · 2026Article
- [Comparative analysis of microbial communities in different oral ecological niches of preschool children].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026Article
- Mapping the oral microbiome in children with oral diseases using next-generation sequencing: a systematic review.Journal of oral microbiology · 2026Review
- Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia.Journal of oral microbiology · 2026Article
- Microbial signatures of dental caries in the incarcerated elderly: a salivary microbiota study in a restricted environment.Journal of oral microbiology · 2026Article
- Multicohort external validation ofFrontiers in cellular and infection microbiology · 2026Article
- Comparative machine learning analysis of saliva and plaque microbiomes in Kuwaitis with type 1 diabetes.Frontiers in microbiology · 2026Article
- L-proline supplementation affects non-volatile flavour perception through oral microbiome metabolic pathways.NPJ science of food · 2025Article
- Article
- MicroSTNet: a spatio-temporal graph-based framework for time-series microbiome analysis.Microbial genomics · 2025Article
- ORMCKB: A Knowledge Database for Personalized Medicine in Deciphering the Oral Microbiome-Disease Axis.Interdisciplinary sciences, computational life sciences · 2025Article
- The link between inflammatory/ SCFA profiles and oral/gut microbiome: an observational study in patients with ST-segment elevation myocardial infarction.Current research in microbial sciences · 2025Article
- Extracellular Phosphate Modulation and Polyphosphate Accumulation byDentistry journal · 2024Article
- Ethnicity-based analysis of supragingival plaque composition and dental health behaviours in healthy subjects without caries.Heliyon · 2024Article
- Intracanal microbiome profiles of two apical periodontitis cases in one patient: A comparison with saliva and plaque profiles.Clinical and experimental dental research · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Dental caries are one of the chronic diseases caused by organic acids made from oral microbes. However, there was a lack of knowledge about the oral microbiome of Korean children. The aim of this study was to analyze the metagenome data of the oral microbiome obtained from Korean children and to discover bacteria highly related to dental caries with machine learning models. Saliva and plaque samples from 120 Korean children aged below 12 years were collected. Bacterial composition was identified using Illumina HiSeq sequencing based on the V3-V4 hypervariable region of the 16S rRNA gene. Ten major genera accounted for approximately 70% of the samples on average, including
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Registered trials
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