Evidence map›Paper›PMID 34441017›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Diagnostic Accuracy and Prognostic Value of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Septic Patients outside the Intensive Care Unit.

Silvia Spoto, Domenica Marika Lupoi, Emanuele Valeriani, Marta Fogolari, Luciana Locorriere, Giuseppina Beretta Anguissola, Giulia Battifoglia, Damiano Caputo, Alessandro Coppola, Sebastiano Costantino and 2 more

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  13. The Ability of NEWS2 to Detect Sepsis in Adult Patients With Positive Blood Cultures.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Silvia SpotoDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Domenica Marika LupoiDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Emanuele ValerianiDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Marta FogolariUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Luciana LocorriereDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Giuseppina Beretta AnguissolaDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Giulia BattifogliaDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Damiano CaputoDepartment of Surgery, University Campus Bio-Medico of Rome, 00128 Roma, Italy.ORCID 0000-0001-7058-1945
Alessandro CoppolaDepartment of Surgery, University Campus Bio-Medico of Rome, 00128 Roma, Italy.ORCID 0000-0002-5550-1756
Sebastiano CostantinoDiagnostic and Therapeutic Medicine Department, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Massimo CiccozziUnit of Medical Statistics and Molecular Epidemiology, University Campus Bio-Medico of Rome, 00128 Roma, Italy.
Silvia AngelettiUnit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, 00128 Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NeutrophilsSepsisBlood PlateletsHumansIntensive Care UnitsLymphocytesPrognosisRetrospective StudiesROC CurveC-reactive proteinMRproAdrenomedullinneutrophil-to-lymphocyteplatelet-to-lymphocyteprocalcitoninquick-sequential organ failure assessmentsepsisseptic shocksequential organ failure assessmentsystemic inflammatory response syndrome

Identifiers

PMID34441017
PMCPMC8399559

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.