ReviewMedicina (Kaunas, Lithuania)2021
Lidocaine: A Local Anesthetic, Its Adverse Effects and Management.
Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Allergic Reactions in Dental Practice: Classification of Medicines, Mechanisms of Action, and Clinical Manifestations.Clinical reviews in allergy & immunology · 2025Pooled it
- Comparison of Compound Lidocaine Cream and Lidocaine-Prilocaine Cream for Pain Management in Facial Rejuvenation: A Randomized Controlled Trial.Journal of cosmetic dermatology · 2026Trial
- 5.6% lidocaine aerosol anesthesia for supragingival ultrasonic scaling in patients with chronic periodontitis or dental plaque-induced gingivitis.Scientific reports · 2025Trial
- Balanced opioid-free anesthesia with lidocaine and esketamine versus balanced anesthesia with sufentanil for gynecological endoscopic surgery: a randomized controlled trial.Scientific reports · 2024Trial
- Pharmacological assessment of drugs retained in the 1Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Emergency Preparedness for Local Anesthetic Systemic Toxicity in Dental Practice: Dentists' Knowledge, Awareness, and Institutional Availability of Lipid Emulsion Therapy.Healthcare (Basel, Switzerland) · 2026Article
- Enhanced Analgesic Outcomes with Low-dose Dexmedetomidine and Lignocaine-Adrenaline in Pediatric Inferior Alveolar Nerve Block: A Randomized Trial.International journal of clinical pediatric dentistry · 2026Article
- Comparative Evaluation of Hydrogel Dip-Coating on Cone and Pyramid Microneedle Arrays Fabricated by LCD 3D Printing.Pharmaceutics · 2026Article
- Acute respiratory distress syndrome after administration of lidocaine in bronchoscopy.Lung India : official organ of Indian Chest Society · 2026Article
- Assessment of Dental Students' and General Dentistry Residents' Knowledge Regarding the Management of Anaphylactic Shock in the Dental Practice: A Single-Centre Study in Romania.Dentistry journal · 2026Article
- Article
- Adverse events associated with local anaesthetic use in musculoskeletal injection therapy: a scoping review.BMJ open sport & exercise medicine · 2026Article
- The Gap Between Suspected Local Anesthetic Allergy and Formal Diagnostic Evaluation.Journal of asthma and allergy · 2026Article
- Transient Stroke-Like Symptoms Following Subcutaneous Lidocaine Administration: A Case Report.Cureus · 2025Article
- Suzetrigine - A Novel FDA-Approved Analgesic - Opportunities, Challenges and Future Perspectives: A Perspective Review.Health science reports · 2025Article
- Viscoelastic Properties and Enzymatic Degradation of Crosslinked Hyaluronic Acid for Deep Dermal Filler Use.Gels (Basel, Switzerland) · 2025Article
- First time inflatable penile prostheses performed under local anesthesia: a single surgeon series suggests ways to improve both the patient and surgeon experience.International journal of impotence research · 2025Review
- A mosquito proboscis-inspired cambered microneedle patch for ophthalmic regional anaesthesia.Journal of advanced research · 2025Article
- Analysis of the effects of cystic cavity flushing with lidocaine during ultrasound-guided anhydrous ethanol sclerotherapy in the treatment of ovarian endometrioma.Quantitative imaging in medicine and surgery · 2025Article
- Comprehensive management evaluation of anaphylactic shock in dental clinics across developing countries.International journal of emergency medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The most widely used medications in dentistry are local anesthetics (LA), especially lidocaine, and the number of recorded adverse allergic responses, particularly of hazardous responses, is quite low. However, allergic reactions can range from moderate to life-threatening, requiring rapid diagnosis and treatment. This article serves as a review to provide information on LA, their adverse reactions, causes, and management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.