Evidence map›Paper›PMID 34440977›Full record

SynthesisMedicina (Kaunas, Lithuania)2021

The Impact of Bipolar Disorder on Couple Functioning: Implications for Care and Treatment. A Systematic Review.

Jean-Michel Azorin, Antoine Lefrere, Raoul Belzeaux

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Development of the Japanese version of the Manchester short assessment of quality of life (MANSA) among people with self-reported severe mental illness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
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  7. Article
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  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jean-Michel AzorinDepartment of Psychiatry, Sainte Marguerite Hospital, 13009 Marseille, France.
Antoine LefrereDepartment of Psychiatry, Sainte Marguerite Hospital, 13009 Marseille, France.
Raoul BelzeauxDepartment of Psychiatry, Sainte Marguerite Hospital, 13009 Marseille, France.
Hôpital Sainte-Marguerite · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

If there is an abundant literature on the impact of bipolar illness on the family and/or caregivers of patients, few studies have addressed its impact on marital relationship and couple functioning. Uncovering information relating specifically to this topic may be particularly relevant due to the unusually high divorce rate among individuals with bipolar disorder. We therefore conducted a systematic literature search to evaluate the existing data on bipolar disorder and marital issues, with a special focus on the help and support that can be provided by mental health professionals in this regard. We identified quantitative studies with pre-defined outcomes as well as qualitative investigations trying to understand the experiences of partners. A total of 27 articles were included in the review. The literature was found to capture the impact of bipolar disorder on partners as well as on the marital relationship itself or the children. Bipolar illness has a negative impact on the lives of partners including self-sacrifice, caregiver burden, emotional impact, and health problems. This negative impact can be aggravated by a lack of care and a lack of information from health personnel. The negative impact on the relationship includes volatility in the relationship, stigmatization, dissatisfaction with sexual life, and lower rates of childbearing. Negative impacts are likely to favor disease relapses for the patient. Children may also be negatively impacted. However, the illness may sometimes have positive impacts such as personal evolution, strengthening relationship, or new hope and perspectives. Based on these findings, the interventions of mental health professionals should be aimed at minimizing the negative impacts while favoring the positive ones.

Indexed as

Bipolar DisorderCaregiversChildEmotionsHumansbipolar disorderchildrencouple functioningcouple relationshipcouple therapymarital relationshippartnerspouse

Identifiers

PMID34440977
PMCPMC8400362
OpenAlexW3184517460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.